Lysosomes : biology, diseases, and therapeutics /

Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development.- Explores basic principles and properties of lysosomes that allow them t...

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Bibliographic Details
Uniform Title:Lysosomes (Maxfield)
Other Authors: Maxfield, Frederick R. (Editor), Willard, James M., 1955- (Editor), Lu, Shuyan, 1971- (Editor)
Format: eBook
Language:English
Published: Hoboken, New Jersey : John Wiley & Sons, Inc., [2016]
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development.- Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates - Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair- Introduces new pathways in therapeutic development and new mechanisms in drug development.
Physical Description:1 online resource
Bibliography:Includes bibliographical references and index.
ISBN:9781118978320
1118978323
9781118978306
1118978307
9781118978313
1118978315
1118645154
9781118645154