Peripheral nerve disorders : pathology & genetics /
Peripheral Nerve Disorders: Pathology and Genetics is a definitive, clinically-oriented guide to the pathology of peripheral nerve disorders. These commonly seen neurological challenges have many causes and accurate diagnosis is often necessary via pathological analysis. New techniques exploiting mo...
| Uniform Title: | Peripheral nerve disorders (Vallat) |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
Chichester, West Sussex, UK :
Wiley Blackwell,
2014.
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Peripheral nerve disorders: pathology and genetics; Copyright; Contents; Contributor list; Preface; Abbreviations; Chapter 1 Clinical assessment and classification of peripheral nerve diseases; Pathophysiology; Clinical examination; Pattern of distribution of nerve involvement; Medical history; Clinical presentation; Examination; Electrophysiological examination; Electromyography; Nerve conduction studies; Laboratory investigations in peripheral neuropathies; Clinical classification of peripheral neuropathies; Indications for nerve biopsy; Nerve selection.
- Indications for and information from nerve biopsyReferences; Chapter 2 Combined muscle and nerve biopsy; Introduction; Technique; Results; Vasculitis; Intra-vascular lymphoma; Sarcoidosis; Amyloid polyneuropathies; Mitochondrial cytopathies; Storage diseases; Cholesterol emboli; References; Chapter 3 Cutaneous nerve biopsy; Introduction; Technique; Skin biopsy and location; Tissue preparation; Quantification of intra-epidermal nerve fiber density; Results; Morphology of intra-epidermal and dermal nerve fibers; Autonomic innervation.
- Examples of the diagnostic value of cutaneous nerve biopsy in peripheral nerve diseaseSmall fiber neuropathy; Diabetic neuropathy; Hereditary neuropathies; Demyelinating and vasculitic neuropathies; Nerve regeneration; Conclusions and recommendations for practical application; References; Chapter 4 Methods for examination of peripheral nerve; General considerations; Nerve biopsy; Postmortem examination; Methods for evaluating nerve biopsies; Routine histology (paraffin embedding); Immunohistochemistry; Plastic-resin embedding; Frozen sections for immunofluorescence.
- Dissociation of fibers (nerve teasing)Frozen specimens for molecular analysis; Electron microscopy; Quantitative and morphometric analyses; References; Chapter 5 Complications from nerve biopsy; Introduction: My nerve biopsy; Frequency of complications; When to perform a nerve biopsy; Predicting complications; Reducing complications; References; Chapter 6 Anatomy of the peripheral nerve; Introduction; Normal anatomy of peripheral nerves; The nerve trunk; Axons; Myelinated nerve fibers; Unmyelinated axons; End organs; Sensory endings; Variations according to age; Development; Age changes.