rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Metal-based neurodegeneration
    sub title: from molecular mechanisms to therapeutic strategies
  name:
    name part: Crichton, Robert R.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Ward, Roberta J.
    role:
      role term: author.
  type of resource: text
  genre: bibliography
  genre: Electronic books.
  origin info:
    place:
      place term: enk
    date issued: 2014
    edition: Second edition.
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (439 pages) : illustrations (chiefly color)
  abstract: Neurodegenerative diseases of the human brain appear in various forms, resulting in disorders of movement and coordination, cognitive deterioration and psychiatric disturbances. Many of the key factors leading to neurodegenerative diseases are similar, including the dysfunction of metal ion homeostasis, redox-active metal ions generating oxidative stress, and intracellular inclusion bodies. Metal-based Neurodegeneration presents a detailed survey of the molecular origins of neurodegenerative diseases. Each chapter is dedicated to a specific disease, presenting the latest scient.
  table of contents: Brain function, physiology, and the blood-brain barrier -- Role of metal ions in brain function, metal transport, storage, and homeostasis -- Immune system and neuroinflammation -- Oxidative stress in neurodegenerative diseases -- Aging and mild cognitive impairment, MCI -- Parkinson's disease -- Alzheimer's disease -- Huntington's disease and polyglutamine expansion neurodegenerative diseases -- Friedreich's ataxia and diseases associated with expansion of non-coding triplets -- Creutzfeldt-Jakob and other prion diseases -- Amyotropic lateral sclerosis -- Alcoholic brain damage -- Other neurological diseases -- Therapeutic strategies to combat the onset and progression of neurological diseases.
  note: Robert Crichton and Roberta Ward.
  note: Includes bibliographical references and index.
  subject:
    topic: Nervous system
    topic: Degeneration
    topic: Etiology
  subject:
    topic: Brain
    topic: Pathophysiology
  subject:
    topic: Oxidative stress
  subject:
    topic: Metals
    topic: Health aspects
  subject:
    topic: Neurodegenerative Diseases
    topic: etiology
  subject:
    topic: Neurodegenerative Diseases
    topic: metabolism
  subject:
    topic: Brain
    topic: physiology
  subject:
    topic: Metals
    topic: adverse effects
  subject:
    topic: Oxidative Stress
  classification: RC365 .C75 2014
  classification: 616.8/0471
  classification: WL 358.5
  related item:
    title info:
      title: Metal-based neurodegeneration
    name:
      name part: Crichton, Robert R.
    origin info:
      publisher: Chichester, West Sussex, U.K. : John Wiley & Sons, 2013
      edition: 2nd ed.
    identifier: (DLC) 2012048288
  identifier: 9781118553497
  identifier: 1118553497
  identifier: 9781118553480
  identifier: 1118553489
  identifier: 9781118553503
  identifier: 1118553500
  identifier: 9781118553510
  identifier: 1118553519
  identifier: 9781119977148
  identifier: 1119977142
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: NhCcYBP
    record creation date: 121206
    record change date: 20260214213605.4
    record identifier: in00004680345
    language of cataloging:
      language term: eng