rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Hydrophilic interaction chromatography
    sub title: a guide for practitioners
  name:
    name part: Olsen, Bernard A.
    name part: 1953-
  name:
    name part: Pack, Brian W.
    name part: 1970-
    role:
      role term: author.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: nju
    date issued: 2013
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource : illustrations
  abstract: "This book provides background information, guidance for method development, and a discussion of applications in the field of hydrophilic interaction chromatography (HILIC.) The book serves as a valuable reference tool for scientists confronted with an analysis problem involving polar compounds to determine if HILIC would be a good choice to pursue and helps them in choosing initial experimental conditions. The book gives a detailed description of the HILIC retention mechanisms and specific information regarding application areas spanning a wide range of industries. Topics include: HILIC retention mechanisms, Stationary Phases for HILIC, HILIC Method Development, Pharmaceutical and Other Applications of HILIC, HILIC for Drug Discovery, HILIC in Two-Dimensional Separations"--
  abstract: "Covers in detail HILIC retention mechanism, including background on the HILIC mode, what differences it from other HPLC modes, and retention mechanisms that can come into play"--
  table of contents: Separation mechanisms in hydrophilic interaction chromatography -- Stationary phases for HILIC -- HILIC method development -- Pharmaceutical applications of hydrophilic interaction chromatography -- Hydrophilic interaction chromatography (HILIC) for drug discovery -- Advances in hydrophilic interaction chromatography (HILIC) for biochemical applications -- HILIC-MS for targeted metabolomics and small molecule bioanalysis -- HILIC for food, environmental, and other applications -- Theory and practice of two-dimensional liquid chromatography separations involving the HILIC mode of separation.
  note: edited by Bernard A. Olsen, Brian W. Pack.
  note: Machine generated contents note: Chapter 1. Separation Mechanisms in Hydrophilic Interaction Chromatography 1.1 Introduction 1.2 Historical Background. Recognition of the contribution of partition, ion exchange and reversed-phase interactions to the retention process 1.3 Recent studies on the contributory mechanisms to HILIC retention 1.3.1 Overview 1.3.2 Contribution of adsorption and partition to HILIC separations 1.3.3 Further studies on the contribution of ionic retention in HILIC 1.3.3.1 Introduction 1.3.3.2 Mobile phase considerations for the separation of ionogenic compounds 1.3.3.3. Ionisation state of the column as a function of pH 1.3.3.4 Quantitation of ionic retention effects on different columns 1.3.4 Reversed-phase retention on bare silica 1.3.5 Electrostatic Repulsion Hydrophilic Interaction Chromatography (ERLIC)- a new separation mode in HILIC. 1.4 Conclusions Chapter 2. Stationary Phases for HILIC 2.1 Introduction 2.2 HILIC stationary phases 2.2.1 Underivatized silica 2.2.1.1 Totally porous silica particles 2.2.1.2 Superficially porous (core shell) silica particles 2.2.1.3 Monolithic silica 2.2.1.4 Ethylene Bridged Hybrids (BEH) 2.2.2 Derivatized silica 2.2.2.1 Neutral derivatized silica 2.2.2.2 Zwitterionic derivatized silica 2.2.2.3 Positively charged derivatized silica 2.2.2.4 Negatively charged derivatized silica 2.2.3 Non-silica phases 2.2.3.1 Amino phases 2.2.3.2 Sulfonated S-DVB phases 2.3 Commercial HILIC phases 2.3.1 Efficiency comparison 2.3.2 Retention and selectivity comparisons 2.4 Conclusions Chapter 3. HILIC Method Development 3.1 Introduction 3.2 General method development considerations 3.2.1 Method objectives 3.2.2 Sample consideration 3.2.3 Systematic method development 3.3 Method development strategies 3.3.1 Systematic approach to column screening 3.3.2 Optimization of method parameters 3.3.2.1 Final column selection 3.3.2.2 Organic solvents 3.3.2.3 Mobile phase pH 3.3.2.4 Buffer types and concentration 3.3.2.5 Column temperatur…
  note: Includes bibliographical references and index.
  subject:
    topic: Hydrophilic interaction liquid chromatography
  classification: QD79.C454 H93 2013
  classification: 543/.84
  classification: SCI013010
  related item:
    title info:
      title: Hydrophilic interaction chromatography
    origin info:
      publisher: Hoboken, New Jersey : John Wiley & Sons, Inc., [2013]
    identifier: (DLC) 2012027157
  related item:
    title info:
      title: Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications
  identifier: 9781118495230
  identifier: 1118495233
  identifier: 9781118495216
  identifier: 1118495217
  identifier: 9781118495247
  identifier: 1118495241
  identifier: 9781118054178
  identifier: 1118054172
  identifier: 2017285041
  identifier: EB00063751 Recorded Books
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: DLC
    record creation date: 170530
    record change date: 20260214211003.3
    record identifier: in00004680194
    language of cataloging:
      language term: eng