http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
Thomas' hematopoietic cell transplantation
Annotation -- Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, fieldleading resource. -- Extensive coverage of the field, from the scientific basis for stemcell transplantation to the future direction of research -- Combines the knowledge and expertise of over 170 international specialists across 106 chapters -- Includes new chapters addressing basic science experiments in stemcell biology, immunology, and tolerance -- Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decisionmaking -- Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more.
Volume 1 ; Title Page; Copyright Page; Contents; Contributors; Preface to the First Edition; Preface to the Fifth Edition; Tribute; List of Abbreviations; Section 1 History and Use of Hematopoietic Cell Transplantation; Chapter 1 A History of Allogeneic and Autologous HematopoieticCell Transplantation ; How it all began; History of allogeneic HCT; 1949-1956: The humoral versus the cellular hypotheses; 1956-1959: Early efforts in clinical marrow transplantation; 1955-1967: Progress in animal models of allogeneic HCT; 1968-1975: The beginning of the modern era of human marrow transplantation.
1976-1989: Widening application of allogeneic marrow grafting for human patients1989-1999: Progress in the prevention and therapy of CMV disease. New sources of grafts for allogeneic HCT; 2000-present: Reduced intensity regimens (RIC) allow transplantation of elderly and medically infirm patients. Hematologic grafts induce tolerance for solid organ transplantation; History of autologous HCT; 1958-1964: From pre-clinical studies to first clinical transplant efforts ; 1978-1995: The beginning of an era of promising results in autologous HCT.
1986-2004: Circulating stem cells and cloned hematopoietic growth factors1982-2001: Testing for minimal residual disease and efforts to purge grafts for autologous HCT; 1986-1999: High-dose chemotherapy and transplantation of autologous hematopoietic cells for patients with breast cancer ; 1993-present: Research to improve preparatory regimens and efforts to consolidate post-HCT remissions ; Conclusion; References; Chapter 2 Uses and Growth of Hematopoietic Cell Transplantation; Introduction; Changing indications for HCT; Changes in patient selection; Hematopoietic cell sources.
Autologous transplantationAllogeneic transplantation; Transplantation regimens and supportive care; Long-term survivors; Addressing barriers to use of HCT; Assessing and improving results of HCT; References; Section 2 Scientific Basis or Hematopoietic Cell Transplantation; Section 2a Hematopoiesis and Stem Biology Transplantation; Chapter 3 Generation of Definitive Engraftable Hematopoietic Stem Cells from Human Pluripotent Stem Cells; Introduction; Generation of HSCs from ESCs; What have we learned from murine ESCs?; Derivation of HSCs from hPSCs; Derivation of hemangioblasts from hESCs.
Derivation of blood-specific lineages from hPSCsT cells; B cells; NK cells; Macrophages; Dendritic cells; Erythroid cells; Megakaryocytes/platelets; Isolation and/or expansion of hPSC-derived HSCs; Are PSC-derived hematopoietic progenitors capable of engraftment and hematopoietic repopulation?; Transplantation of HSCs derived from mPSCs; Transplantation of HSCs derived from human PSCs; Can we generate immunologically compatible HSCs?; Creation of a global hPSC bank; Immune privileged?; Pluripotent stem cells tailor-made by reprogramming patients' somatic cells (iPS).
edited by Frederick R. Appelbaum, Stephen J. Forman, Robert S. Negrin, Joseph H. Antin.
Includes bibliographical references and index.
Chichester, West Sussex, United Kingdom ; Hoboken, NJ : John Wiley & Sons Inc., 2015