Viral infections and global change /
A timely exploration of the impact of global change on the emergence, reemergence, and control of vector-borne and zoonotic viral infections From massively destructive ""superstorms"" to rapidly rising sea levels, the world media is abuzz with talk of the threats to civilization...
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| Format: | eBook |
| Language: | English |
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Hoboken, New Jersey :
Wiley,
[2014]
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| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Machine generated contents note: pt. I GENERAL ASPECTS
- 1. Climate Change and Vector-Borne Viral Diseases / Peng Bi
- 1.1. Introduction
- 1.2. Epidemiology of VVD
- 1.2.1. What are VVD?
- 1.2.2. Temporal
- spatial distribution of VVD around the world
- 1.2.3. Factors that affect the transmission
- 1.3. Association between climatic variables and emerging VVD
- 1.3.1. Dengue fever
- 1.3.2. Yellow fever
- 1.3.3. Viral encephalitis: Japanese encephalitis, Murray Valley encephalitis, and West Nile encephalitis
- 1.3.4. Ross River fever and Barmah Forest fever
- 1.3.5. Chikungunya fever
- 1.3.6. Rift Valley fever
- 1.3.7. Omsk hemorrhagic fever and Crimean
- Congo hemorrhagic fever
- 1.4. Invasion of nonzoonotic VVD to humans
- 1.5. Implications and recommendations for prevention and control
- References
- 2. Impact of Climate Change on Vector-Borne Arboviral Episystems / Jonathan F. Day
- 2.1. Introduction
- 2.2. complex factors influencing mosquito-borne arbovirus episystems
- 2.3. West Nile virus
- 2.3.1. Influence of climate on the North American WNV episystem
- 2.3.2. Effects of future changes in climate on the North American WNV episystem
- 2.4. Dengue in Florida
- 2.4.1. Did climate change play a role in the reemergence of dengue in Florida?
- 2.5. Bluetongue
- 2.5.1. Influence of climate on the European bluetongue episystem
- 2.5.2. role of climate change in the European BTV episystem
- 2.6. Conclusions
- Acknowledgement
- References
- 3. Influence of Climate Change on Mosquito Development and Blood-Feeding Patterns / William K. Reisen
- 3.1. Introduction
- 3.2. Mosquito development
- 3.2.1. Temperature
- 3.2.2. Precipitation
- 3.2.3. Effects of elevated CO2 concentration
- 3.2.4. Photoperiodic cues
- 3.3. Blood-feeding patterns
- 3.3.1. Temperature
- 3.3.2. Humidity
- 3.3.3. Cumulative impact on mosquito-borne viral infections
- References
- 4. Environmental Perturbations That Influence Arboviral Host Range: Insights Into Emergence Mechanisms / William K. Reisen
- 4.1. Introduction
- 4.2. changing environment
- 4.3. Deforestation and the epizootic emergence of Venezuelan equine encephalitis virus
- 4.4. Rice, mosquitoes, pigs, and Japanese encephalitis virus
- 4.5. Culex pipiens complex, house sparrows, urbanization, and west Nile virus
- 4.6. Urbanization, global trade, and the reemergence of chikungunya virus
- 4.7. Conclusions
- References
- 5. Socio-Ecology of Viral Zoonotic Transfer / Sarah Paige
- 5.1. Introduction
- 5.2. Historical perspective
- 5.3. Human
- animal interface
- 5.4. Surveillance
- 5.5. Deforestation and fragmentation
- 5.6. Urbanization
- 5.7. Examples
- 5.7.1. Nipah virus
- 5.7.2. Hendra
- 5.7.3. Influenza
- 5.8. Conclusion
- References
- 6. Human Behavior and The Epidemiology of Viral Zoonoses / Calum N.L. Macpherson
- 6.1. Introduction
- 6.2. Societal changes and the epidemiology of viral zoonoses
- 6.2.1. human-animal relationship
- 6.2.2. Migration and population movements
- 6.2.3. Climate change and vectors
- 6.3. Viral zoonoses and human societal values
- 6.3.1. Individual and collective responsibility
- 6.4. Human behavior and the epidemiology of vector-borne viral zoonoses
- 6.4.1. Yellow fever (urban yellow fever, sylvatic or jungle yellow fever)
- 6.4.2. WNV
- 6.4.3. TBE
- 6.4.4. Encephalitides
- 6.4.5. LAC encephalitis
- 6.4.6. JE
- 6.4.7. Saint Louis encephalitis (SLE)
- 6.4.8. EEE
- 6.4.9. Venezuelan equine encephalitis (VEE)
- 6.5. Human behavior and the epidemiology of respiratory viral zoonoses
- 6.5.1. HeV
- 6.5.2. NIV
- 6.5.3. SARS
- 6.5.4. Influenza H1N1
- 6.5.5. Influenza H5N1
- 6.5.6. Travel and respiratory viral zoonoses
- 6.6. Human behavior and the epidemiology of waterborne viral zoonoses
- 6.6.1. Waterborne zoonotic viruses
- 6.6.2. Epidemiology of waterborne viral zoonoses
- 6.6.3. Prevention and control
- 6.7. Human behavior and the epidemiology of wildlife-associated Viral Zoonoses
- 6.7.1. Case study: bushmeat hunting in Cameroon
- 6.7.2. Epidemiology of viral zoonoses from wildlife
- 6.8. role of human behavior in the control of viral zoonoses
- 6.8.1. Communication
- References
- 7. Global Travel, Trade, And The Spread Of Viral Infections / Douglas W. MacPherson
- 7.1. Introduction
- 7.2. Basic principles
- 7.2.1. Extension
- 7.2.2. Expression
- 7.3. overview of population mobility
- 7.4. dynamics of modern population mobility
- 7.5. Human population mobility and the spread of viruses
- 7.6. biological aspects of population mobility and the spread of viruses
- 7.7. demographic aspects of population mobility and the spread of viruses
- 7.7.1. Elements related to the volume of travel
- 7.7.2. Elements related to disparities in health practices
- 7.7.3. Situations where population mobility and travel can affect The Spread of Viruses
- 7.7.4. Humanitarian and complex emergencies
- 7.7.5. Social and economic aspects of population mobility
- 7.7.6. overview of trade
- 7.7.7. Trade and the spread of viruses
- 7.8. Potential impact of climate change
- 7.9. Conclusion
- References
- 8. Effects of Land-Use Changes and Agricultural Practices on The Emergence and Reemergence of Human Viral Diseases / Richard Coker
- 8.1. Introduction
- 8.2. Ecological and environmental changes
- 8.2.1. Deforestation
- 8.2.2. Habitat fragmentation
- 8.2.3. Structural changes in ecosystems
- 8.3. Agricultural change
- 8.3.1. Agricultural expansion
- 8.3.2. Intensification of livestock production
- 8.4. Demographic changes
- 8.4.1. Urbanization
- 8.5. Land use, disease emergence, and multifactorial causation
- 8.6. Conclusion
- References
- 9. Animal Migration and Risk of Spread of Viral Infections / John Y. Takekawa
- 9.1. Introduction
- 9.1.1. Animal migration and disease
- 9.2. Does animal migration increase risk of viral spread?
- 9.3. Examples of migratory animals and spread of viral disease
- 9.3.1. Birds
- 9.3.2. Mammals
- 9.3.3. Fish and herpetiles
- 9.4. Climate change effects on animal migration and viral zoonoses
- 9.5. Shifts in timing of migration and range extents
- 9.6. Combined effects of climate change, disease, and migration
- 9.7. Conclusions and future directions
- Acknowledgements
- References
- 10. Illegal Animal and (Bush) Meat Trade Associated Risk of Spread of Viral Infections / Bruno Chomel
- 10.1. Introduction
- 10.2. Search strategy and selection criteria
- 10.3. bushmeat trade
- 10.4. Bushmeat hunting and emerging infectious diseases
- 10.5. Risk factors and modes of transmission
- 10.5.1. Human-nonhuman primate overlap
- 10.5.2. Behavioral risks
- 10.6. Conservation and wildlife sustainability
- 10.7. Case study: The role of the bushmeat trade in the evolution of HIV
- 10.8. Illegal trade of domestic animals and exotic pets
- 10.9. Discussion and future directions
- 10.10. Prevention and control: From supply and demand to health education techniques
- 10.11. New technologies
- 10.11.1. Laboratory tools
- 10.11.2. Surveillance tools
- 10.12. Collaboration: Multidisciplinary advances and next steps
- 10.13. Conclusion
- Conflicts of interest
- References
- 11. Biological Significance of Bats as a Natural Reservoir Of Emerging Viruses / Richard A.
- Bowen
- 11.1. Introduction
- 11.2. Bats as exemplars of biodiversity
- 11.3. Bats are reservoir hosts for zoonotic and emerging pathogens
- 11.3.1. Lyssaviruses
- 11.3.2. Henipaviruses
- 11.3.3. Filoviruses
- 11.3.4. Coronaviruses
- 11.3.5. Arboviruses
- 11.4. Contact rate as a driver for emergence of bat-associated zoonoses
- 11.5. Potential impact of climate change on viruses transmitted by bats
- 11.6. Conclusions
- References
- 12. Role and Strategies of Surveillance Networks in Handling Emerging And Reemerging Viral Infections / Carlos Castillo-Salgado
- 12.1. Introduction
- 12.2. Global trend of viral infectious agents and diseases
- 12.3. Recognized importance of public health surveillance
- 12.3.1. Public health surveillance as essential public health functions and core competencies
- 12.4. Definition and scope of public health surveillance
- 12.5. Key functions and uses of disease surveillance
- 12.6. New expansion of surveillance by the IHR-2005
- 12.7. Emergence of new global surveillance networks
- 12.8. Global influenza surveillance and WHO's pandemic influenza preparedness framework
- 12.9. Early warning surveillance systems
- 12.10. Innovative approaches for surveillance
- 12.11. Electronic and web-based information platforms for information reporting, sharing, and dissemination
- 12.12. Real-time and near real-time information
- 12.13. New updated statistical methods for tracking viral and infectious disease outbreaks
- 12.13.1. Use of Geographic Information Systems (GIS) for mapping and geo-referencing public health events and risks of national and global importance
- 12.14. Using proxy and compiled web-based information from different sources
- 12.15. Incorporation of public
- private partnerships in surveillance activities
- 12.16. Use of volunteer sentinel physicians
- 12.17. Improving guidelines and protocols for viral surveillance
- 12.18. Incorporating health situation rooms or strategic command centers for monitoring, analysis, and response in surveillance efforts.
- Note continued: 12.19. Challenges of viral and public health surveillance
- References
- 13. Predictive Modeling of Emerging Infections / Sheri H. Lewis
- 13.1. Introduction
- 13.2. Types of models
- 13.3. Remote sensing and its use in disease outbreak prediction
- 13.4. Approaches to modeling and their evaluation
- 13.5. Examples of prediction models
- 13.5.1. Rift Valley fever
- 13.5.2. Cholera
- 13.5.3. Dengue
- 13.6. Conclusion
- References
- 14. Developments and Challenges in Diagnostic Virology / Giorgio Palu
- 14.1. Introduction
- 14.2. Preparedness
- 14.3. Challenges in diagnosis of emerging viral infections
- 14.4. Approaches to the diagnosis of emerging viral infections
- 14.4.1. Specimen collection
- 14.4.2. Viral culture
- 14.4.3. Viral antigen detection
- 14.4.4. Molecular detection
- 14.4.5. Viral serology
- 14.4.6. Metagenomics and virus discovery
- 14.4.7. POC testing
- 14.5. Conclusions
- Acknowledgement
- References
- 15. Advances in Detecting and Responding to Threats From Bioterrorism And Emerging Viral Infections / Angela Weber
- 15.1. Introduction
- 15.2. Emerging, reemerging, and intentionally emerging diseases
- 15.3. Bioterrorism
- 15.4. Viruses as bioweapons
- 15.5. Impact of biotechnology
- 15.5.1. Mousepox virus
- 15.5.2. Influenza A
- 15.5.3. Synthetic genomes
- 15.6. Deterrence, recognition, and response
- 15.6.1. Deterrence
- 15.6.2. Laboratory Response Network
- 15.6.3. Advances in diagnostics
- 15.6.4. Point-of-care diagnostics
- 15.6.5. PCR
- 15.7. Public health surveillance
- 15.7.1. Passive surveillance
- 15.7.2. Active surveillance
- 15.7.3. Syndromic surveillance
- 15.7.4. Detection of viral infections
- 15.8. Conclusion
- References
- 16. Molecular and Evolutionary Mechanisms of Viral Emergence / Esteban Domingo
- 16.1. Introduction: Biosphere and virosphere diversities
- 16.2. Virus variation as a factor in viral emergence: a role of complexity
- 16.3. High error rates originate quasispecies swarms
- 16.4. Evolutionary mechanisms that may participate in viral disease emergence
- 16.5. Ample genetic and host range variations of fMDV: a human epidemic to be?
- 16.6. arbovirus host alternations: high exposure to environmental modifications
- 16.7. Arenaviruses: As an emerging threat
- 16.8. Conclusion
- Acknowledgement
- References
- 17. Drivers of Emergence and Sources of Future Emerging and Reemerging Viral Infections / Albert D.M.E. Osterhaus
- 17.1. Introduction
- 17.2. Prehistoric and historic unfolding of the drivers of disease emergence
- 17.2.1. Prehistory and before: Microbial adaptation and change
- 17.2.2. Prehistoric human migrations and international travel
- 17.2.3. Domestication, demographic, and behavioral changes
- 17.2.4. Human settlements and changing ecosystems
- 17.2.5. Ancient and medieval times: Commerce, warfare, poverty, and climate
- 17.2.6. Recent past and modern times: Technology and industry
- 17.3. Proximal drivers of disease emergence and sources of future emerging and reemerging viral infections
- 17.4. Further insights from the theory of island biogeography
- References
- 18. Spillover Transmission and Emergence of Viral Outbreaks in Humans / Sunit K. Singh
- 18.1. Introduction
- 18.2. Major anthropogenic factors responsible for spillover
- 18.3. Major viral factors playing a role in spillover
- 18.3.1. Reassortment
- 18.3.2. Recombination
- 18.3.3. Mutation
- 18.4. Intermediate hosts and species barriers in viral transmission
- 18.5. Conclusion
- References
- pt. II SPECIFIC INFECTIONS
- 19. New, Emerging, and Reemerging Respiratory Viruses / Albert D.M.E. Osterhaus
- 19.1. Introduction
- 19.1.1. History
- 19.1.2. Newly discovered human respiratory viruses that recently crossed the species barrier
- 19.2. Influenza viruses
- 19.2.1. Transmission of avian influenza to humans
- 19.2.2. Clinical manifestations
- 19.2.3. Diagnosis
- 19.2.4. Treatment, prognosis, and prevention
- 19.3. Human metapneumovirus
- 19.3.1. Epidemiology
- 19.3.2. Clinical manifestations
- 19.3.3. Diagnosis
- 19.3.4. Treatment, prognosis, and prevention
- 19.4. Human coronaviruses: SARS and non-SARS
- 19.4.1. SARS-CoV outbreak
- 19.4.2. Clinical manifestations of SARS-CoV
- 19.4.3. Diagnosis of SARS-CoV
- 19.4.4. Epidemiology of non-SARS coronaviruses
- 19.4.5. Clinical manifestations of non-SARS coronaviruses
- 19.4.6. Diagnosis of non-SARS coronaviruses
- 19.4.7. Treatment, prognosis, and prevention
- 19.5. Human bocavirus
- 19.5.1. Epidemiology
- 19.5.2. Clinical manifestations
- 19.5.3. Diagnosis
- 19.5.4. Treatment, prognosis, and prevention
- 19.6. KI and WU polyomaviruses
- 19.6.1. Epidemiology
- 19.6.2. Clinical manifestations
- 19.6.3. Diagnosis
- 19.6.4. Prognosis
- 19.7. Nipah and hendra viruses
- 19.7.1. Outbreaks
- 19.7.2. Clinical manifestations and prognosis
- 19.7.3. Diagnosis
- 19.7.4. Treatment and prevention
- 19.8. Conclusion
- 19.9. List of abbreviations
- References
- 20. Emergence of Zoonotic Orthopox Virus Infections / Shigeru Morikawa
- 20.1. Smallpox, a representative orthopoxvirus infection: The eradicated non-zoonotic orthopoxvirus
- 20.1.1. Clinical features
- 20.2. Zoonotic Orthopoxviruses
- 20.2.1. Cowpox
- 20.2.2. Monkeypox
- Acknowledgement
- References
- 21. Biological Aspects of The Interspecies Transmission of Selected Coronaviruses / Linda J. Saif
- 21.1. Introduction
- 21.2. Coronavirus classification and pathogenesis
- 21.3. Natural reservoirs and emergence of new coronaviruses
- 21.4. Alpha-, beta- and gamma coronaviruses: cross-species transmission
- 21.4.1. Alpha-coronaviruses cross-species transmission
- 21.4.2. Beta-coronaviruses cross-species transmission
- 21.4.3. Gamma-coronaviruses cross-species transmission
- 21.5. Anthropogenic factors and climate influence on coronavirus diversity and outbreaks
- 21.6. Conclusion
- References
- 22. Impact of Environmental and Social Factors on Ross River Virus Outbreaks / David O. Harley
- 22.1. Introduction
- 22.2. History of mosquito-borne epidemic polyarthritis outbreaks in australia and the pacific
- 22.3. RRV transmission cycles have a variety of ecologies
- 22.4. Typical environmental determinants of RRV activity
- 22.5. Social determinants of RRV disease activity
- 22.6. Conceptual framework for understanding the influence of environmental and social factors on RRV disease activity
- 22.6.1. Climatic and other variables: pathway a
- 22.6.2. Vertebrate host reservoirs: pathway b
- 22.6.3. Mosquito vectors: pathway c
- 22.6.4. Human behavior and the built environment: pathway d
- 22.6.5. Climatic influences on mosquitoes: pathway e
- 22.6.6. Climatic influences on housing and human behavior: pathway f
- 22.6.7. Climatic influences on immune function: pathway g
- 22.7. Climate Change and RRV
- 22.8. Conclusion
- Acknowledgement
- References
- 23. Infection Patterns and Emergence of O'Nyong-Nyong Virus / Ann M.
- Powers
- 23.1. Introduction
- 23.2. History of outbreaks
- 23.3. Clinical manifestations
- 23.4. Epidemiology
- 23.5. Factors affecting emergence
- 23.5.1. Etiologic agent: viral genomics and antigens encoded
- 23.5.2. Transmission parameters
- 23.5.3. Zoonotic maintenance
- 23.5.4. Environmental influences
- 23.6. Conclusion
- References
- 24. Zoonotic Hepatitis E: Animal Reservoirs, Emerging Risks, and Impact of Climate Change / Jerome Bouquet
- 24.1. Introduction
- 24.2. HEV biology and classification
- 24.3. Pathogenesis in humans
- 24.3.1. Acute hepatitis
- 24.3.2. Chronic hepatitis
- 24.3.3. Fulminant hepatitis
- 24.3.4. Neurologic disorders
- 24.4. Animal Reservoirs
- 24.4.1. HEV in pigs
- 24.4.2. Prevalence of HEV in wild animals
- 24.4.3. Prevalence of HEV in avian, rats, and rabbits
- 24.5. Zoonotic and Interspecies Transmission of HEV and HEV-like viruses
- 24.6. HEV in the environment
- 24.7. Climate change and impact on HEV exposure
- 24.8. Prevention
- 24.9. Conclusion
- Acknowledgement
- References
- 25. Impact of Climate Change on Outbreaks of Arenaviral Infections / James Christopher Clegg
- 25.1. Introduction
- 25.2. Natural history of arenaviruses
- 25.3. Predicted climate changes
- 25.4. Arenaviral diseases and climate change
- References
- 26. Emerging and Reemerging Human Bunyavirus Infections and Climate Change / A. Desiree LaBeaud
- 26.1. Introduction
- 26.2. Bunyaviridae family
- 26.2.1. Hantavirus
- 26.2.2. Nairovirus
- 26.2.3. Orthobunyavirus
- 26.2.4. Phlebovirus
- 26.3. Climate Change and Bunyaviridae: Climatic influences on transmission cycles and subsequent risk for transmission of bunyaviruses
- 26.3.1. Arboviral bunyaviruses
- 26.3.2. Non-arboviral bunyaviruses
- 26.4. Disease spread due to growing geographic distribution of competent vectors
- 26.4.1. Physical movement of vectors
- 26.4.2. Expansion of suitable range
- 26.5. Using climate as a means for outbreak prediction
- 26.5.1. Climatic influences
- 26.5.2. Risk mapping and predictions
- 26.6. Future problems
- References
- 27. Emerging Trend of Astroviruses, Enteric Adenoviruses, and Rotaviruses in Human Viral Gastroenteritis / Carl D. Kirkwood
- 27.1. Introduction
- 27.2. Emerging trends in rotaviruses.
- Note continued: 27.2.1. Rotavirus classification
- 27.2.2. Epidemiology of human rotaviruses
- 27.2.3. Clinical symptoms and pathogenesis
- 27.2.4. Genomic diversity of rotaviruses
- 27.2.5. Rotavirus vaccines and the impact of vaccine introduction on the burden of rotavirus disease
- 27.2.6. Globally emerging rotavirus genotypes
- 27.3. Emerging trends in enteric adenoviruses
- 27.3.1. Adenovirus classification
- 27.3.2. Epidemiology of enteric adenoviruses HAdV-F40 and HAdV-F41
- 27.3.3. Clinical symptoms and pathogenesis
- 27.3.4. Diversity and evolution of enteric adenoviruses
- 27.3.5. Emerging human enteric adenovirus species
- 27.4. Emerging trends in astroviruses
- 27.4.1. Astrovirus classification
- 27.4.2. Epidemiology of HAstVs
- 27.4.3. Clinical symptoms and pathogenesis
- 27.4.4. Diversity and evolution of HAstVs
- 27.4.5. Emerging HAstV species
- References
- 28. Emerging Human Norovirus Infections / Stephanie M. Karst
- 28.1. Introduction
- 28.2. Norovirus epidemiology
- 28.3. Features of norovirus outbreaks
- 28.4. Clinical features of norovirus infection
- 28.5. Host Susceptibility
- 28.6. Effect of increased size of immunocompromised population
- 28.7. Effect of globalization of the food market on norovirus spread
- 28.8. Effect of climate change
- References
- 29. Emergence of Novel Viruses (Toscana, Usutu) in Population And Climate Change / Ana Vazquez
- 29.1. Introduction
- 29.2. TOSV
- 29.2.1. Virus properties and classification
- 29.2.2. Clinical picture and geographical distribution
- 29.2.3. Phylogenetic studies: distribution of genotypes
- 29.2.4. Ecology
- 29.2.5. Laboratory diagnosis
- 29.2.6. Prevention of transmission and treatment
- 29.3. USUV
- 29.3.1. Virus: properties and classification
- 29.3.2. History and geographical distribution
- 29.3.3. Ecology: vector, host, and incidental host
- 29.3.4. Pathology
- 29.3.5. Laboratory diagnosis
- 29.3.6. Phylogenetic studies
- 29.3.7. Treatment, prevention, and surveillance
- 29.4. Conclusions
- Acknowledgement
- References
- 30. Borna Disease Virus and The Search for Human Infection / Juan Carlos de la Torre
- 30.1. Introduction
- 30.2. Long-standing controversy around BDV as a human pathogen
- 30.3. negative is impossible to prove, but do we have enough evidence to stop looking?
- 30.4. Recent improvements in testing for evidence of BDV in human samples
- 30.4.1. Serology
- 30.4.2. Nucleic acid tests
- 30.5. possibilities for clinical expression of human BDV infection are myriad and almost impossible to predict
- 30.6. Epidemiology: the new frontier of human BDV studies?
- 30.7. Where do we go from here?
- Acknowledgement
- References
- 31. Tick-Transmitted Viruses and Climate Change / Ivo Rudolf
- 31.1. Introduction
- 31.2. Ticks in nature
- 31.3. Family Flaviviridae
- 31.3.1. Tick-borne encephalitis virus
- 31.3.2. Louping ill virus
- 31.3.3. Powassan virus
- 31.3.4. Omsk hemorrhagic fever virus
- 31.3.5. Kyasanur Forest disease virus
- 31.4. Family Bunyaviridae
- 31.4.1. Crimean-Congo hemorrhagic fever virus
- 31.4.2. Henan virus
- 31.4.3. Bhanja virus
- 31.4.4. Keterah virus
- 31.5. Family Reoviridae
- 31.5.1. Colorado tick fever virus
- 31.5.2. Kemerovo virus
- 31.5.3. Tribec virus
- 31.6. Family Orthomyxoviridae
- 31.6.1. Thogoto virus
- 31.6.2. Dhori virus
- 31.7. Other tick-transmitted viruses
- 31.8. Conclusions
- Acknowledgements
- References
- 32. Tick
- Virus Interface / Marshall E. Bloom
- 32.1. Introduction
- 32.2. Viruses within the tick vector
- 32.2.1. Impact of virus infection on ticks
- 32.2.2. Impact of the tick vector on viruses
- 32.2.3. Tick immunity
- 32.2.4. Other mediators of immunity
- 32.3. Saliva-assisted transmission
- 32.4. Summary and future directions
- 32.4.1. Generation of tick cell lines
- 32.4.2. role of endosymbionts and coinfections
- 32.4.3. Tick innate immunity
- 32.4.4. Identification and characterization of viral SAT factors
- 32.4.5. Viral persistence in tick vectors
- 32.4.6. impact of climate change on tick vectors and tick-borne diseases
- Acknowledgements
- References.