Solid support oligosaccharide synthesis and combinatorial carbohydrate libraries /

Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research in bioorganic chemistry. Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries addresses the exciting expectation that soli...

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Bibliographic Details
Other Authors: Seeberger, Peter H., 1966-
Format: eBook
Language:English
Published: New York : Wiley, ©2001.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 0 0 |a Solid support oligosaccharide synthesis and combinatorial carbohydrate libraries /  |c edited by Peter H. Seeberger. 
260 |a New York :  |b Wiley,  |c ©2001. 
300 |a 1 online resource (xii, 308 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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504 |a Includes bibliographical references and index. 
505 0 |a Solid-phase carbohydrate synthesis : the early work / Wilm-Christian Haase and Peter H. Seeberger -- The glycal assembly method on solid supports : synthesis of oligosaccharides and glycoconjugates / Pier F. Cirillo and Samuel J. Danishefsky -- The sulfoxide glycosylation method and its application to solid-phase oligosaccharide synthesis and the generation of combinatorial libraries / Carol M. Taylor -- The use of O-glycosyl trichloroacetimidates for the polymer-supported synthesis of oligosaccharides / Laurent Knerr and Richard R. Schmidt -- Synthesis of oligosaccharides on solid support using thioglycosides and pentenyl glycosides / Valentin Wittmann -- Solid-phase oligosaccharide synthesis using glycosyl phosphates / Wilm-Christian Haase, Obadiah J. Plante, and Peter H. Seeberger -- Stereoselective [beta]-mannosylation on polymer support / Yukishige Ito and Hiromune Ando -- Tools for on-bead monitoring and analysis in solid-phase oligosaccharide synthesis / Wilm-Christian Haase, Peter H. Seeberger, and Susan S. Pochapsky -- Polyethyleneglycol [omega]-monomethylether (MPEG)-supported solution-phase synthesis of oligosaccharides / Jiri J. Krepinsky and Stephen P. Douglas -- Two-direction glycosylations for the preparation of libraries of oligosaccharides / Geert-Jan Boons and Tong Zhu -- Carbohydrate libraries in solution using thioglycosides : from multistep synthesis to programmable, one-pot synthesis / Eric E. Simanek and Chi-Huey Wong -- Carbohydrate libraries by the random glycosylation approach / Osamu Kanie and Ole Hindsgaul -- Solid-phase synthesis of biologically important glycopeptides / Nicole Bézay and Horst Kunz -- Preparation and screening of glycopeptide libraries / Phaedria M. St. Hilaire, Koen M. Halkes, and Morten Meldal. 
588 0 |a Print version record. 
520 |a Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research in bioorganic chemistry. Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries addresses the exciting expectation that solid-phase assembly of oligosaccharides will have a fundamental impact on the field of glycobiology. This publication details the methodologies currently investigated for the attachment of carbohydrates to beads, synthesis including coupling strategies, and removal of the product from beads. 
650 0 |a Oligosaccharides  |x Synthesis. 
650 0 |a Glycoconjugates. 
650 0 |a Combinatorial chemistry. 
650 0 |a Solid-phase synthesis. 
650 2 |a Glycoconjugates 
655 4 |a Electronic books. 
700 1 |a Seeberger, Peter H.,  |d 1966- 
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880 0 |6 505-00  |a Solid-phase carbohydrate synthesis : the early work / Wilm-Christian Haase and Peter H. Seeberger -- The glycal assembly method on solid supports : synthesis of oligosaccharides and glycoconjugates / Pier F. Cirillo and Samuel J. Danishefsky -- The sulfoxide glycosylation method and its application to solid-phase oligosaccharide synthesis and the generation of combinatorial libraries / Carol M. Taylor -- The use of O-glycosyl trichloroacetimidates for the polymer-supported synthesis of oligosaccharides / Laurent Knerr and Richard R. Schmidt -- Synthesis of oligosaccharides on solid support using thioglycosides and pentenyl glycosides / Valentin Wittmann -- Solid-phase oligosaccharide synthesis using glycosyl phosphates / Wilm-Christian Haase, Obadiah J. Plante, and Peter H. Seeberger -- Stereoselective β-mannosylation on polymer support / Yukishige Ito and Hiromune Ando -- Tools for "on-bead" monitoring and analysis in solid-phase oligosaccharide synthesis / Wilm-Christian Haase, Peter H. Seeberger, and Susan S. Pochapsky -- Polyethyleneglycol [omega]-monomethylether (MPEG)-supported solution-phase synthesis of oligosaccharides / Jiri J. Krepinsky and Stephen P. Douglas -- Two-direction glycosylations for the preparation of libraries of oligosaccharides / Geert-Jan Boons and Tong Zhu -- Carbohydrate libraries in solution using thioglycosides : from multistep synthesis to programmable, one-pot synthesis / Eric E. Simanek and Chi-Huey Wong -- Carbohydrate libraries by the random glycosylation approach / Osamu Kanie and Ole Hindsgaul -- Solid-phase synthesis of biologically important glycopeptides / Nicole Bézay and Horst Kunz -- Preparation and screening of glycopeptide libraries / Phaedria M. St. Hilaire, Koen M. Halkes, and Morten Meldal. 
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