Generation and effector functions of regulatory lymphocytes /

Over the last several years, immunologists have re-discovered the importance of regulatory lymphocytes, formerly termed 'supressor cells. Many recent reports have documented their existence, effector functions and poetntial therapeutic benefits in autoimmunity and transplantation. However, even...

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Bibliographic Details
Other Authors: Bock, Gregory, Goode, Jamie
Format: eBook
Language:English
Published: Chichester, England ; Hoboken, N.J. : Wiley, ©2003.
Series:Novartis Foundation symposium ; 252.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Thymic generation and selection of CD25CD4 regulatory T cells : implications of their broad repertoire and high self-reactivity for the maintenance of immunological self-tolerance / Shimon Sakaguchi, Shohei Hori, Yoshinori Fukui, Takehiko Sasazuki, Noriko Sakaguchi and Takeshi Takahashi
  • Control of T cell activation by CD4CD25⁺ suppressor T cells / Ethan M. Shevach, Ciriaco A. Piccirillo, Angela M. Thornton and Rebecca S. McHugh
  • Regulation of experimental autoimmune encephalomyelitis (EAE) by CD4⁺CD25⁺ regulatory T cells / Adam P. Kohm, Pamela A. Carpentier and Stephen D. Miller
  • The role of CD28 and CTLA4 in the function and homeostasis of CD4⁺CD25⁺ regulatory T cells / Elisa Boden, Qizhi Tang, Helene Bour-Jordan and Jeffrey A. Bluestone
  • CD4⁺CD25⁺ regulatory cells from human peripheral blood express very high levels of CD25 ex vivo / Clare Baecher-Allan, Julia A. Brown, Gordon J. Freeman and David A. Hafler
  • Control of immune pathology by regulatory T cells / Fiona Powrie, Simon Read, Christian Mottet, Holm Uhlig and Kevin Maloy
  • Type 1 T regulatory cells and their relationship with CD4⁺CD25⁺ T regulatory cells / Maria Grazia Roncarolo, Silvia Gregori and Megan Levings
  • (Pro)insulin-specific regulatory T cells / Leonard C. Harrison, Natasha R. Solly and Nathan R. Martinez
  • CD1d-restricted NKT regulatory cells: functional genomic analyses provide new insights into the mechanisms of protection against type 1 diabetes / Qing-Sheng Mi, Craig Meagher and Terry L. Delovitch
  • Seven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune system / Eli Sercarz, Emanual Maverakis, Peter van den Elzen, Loui Madakamutil and Vipin Kumar
  • Regulatory cells in transplantation / Kathryn J. Wood, Hidetake Ushigome, Mahzuz Karim, Andrew Bushell, Shohei Hori and Shimon Sakaguchi
  • CD4⁺ regulatory T cells in chronic viral infection / Kim J. Hasenkrug
  • Modulation of T cell responses after cross-talk between antigen presenting cells and T cells: a give-and-take relationship / Marca H.M. Wauben, Esther N.M. 't Hoen and Leonie S. Taams
  • Dendritic cells: controllers of the immune system and a new promise for immunotherapy / Jacques Banchereau, Joseph Fay, Virginia Pascual and A. Karolina Palucka
  • Regulation of viral and autoimmune responses / Chrystelle Asseman and Matthias von Herrath
  • Notch signalling in the peripheral immune system / Margaret J. Dallman, Brian Champion and Jonathan R. Lamb
  • CD3 antibody treatment stimulates the functional capability of regulatory T cells / Lucienne Chatenoud
  • The role of dendritic cells in regulating mucosal immunity and tolerance / Allan McI Mowat, Anne M Donachie, Lucy A. Parker, Neil C. Robson, Helen Beacock-Sharp, Lindsay J. McIntyre, Owain Millington and Fernando Chirdo.