rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Meta-analysis of controlled clinical trials
  name:
    name part: Whitehead, Anne
    name part: 1950-
    role:
      role term: creator
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: enk
    place:
      place term: Chichester
    place:
      place term: New York
    publisher: John Wiley & Sons
    date issued: ©2002
    date issued: 2002
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xiv, 336 pages)
  abstract: Over the last twenty years there has been a dramatic upsurge in the application of meta-analysis to medical research. This has mainly been due to greater emphasis on evidence-based medicine and the need for reliable summaries of the vast and expanding volume of clinical research. At the same time there have been great strides in the development and refinement of the associated statistical methodology. This book describes the planning, conduct and reporting of a meta-analysis as applied to a series of randomized controlled clinical trials.
  table of contents: The role of meta-analysis -- Retrospective and prospective meta-analyses -- Fixed effects versus random effects -- Individual patient data versus summary statistics -- Multicentre trials and meta-analysis -- Protocol development -- Outcome measures and baseline information -- Sources of data -- Study selection -- Data extraction -- Statistical analysis -- Analysis population -- Missing data at the subject level -- Analysis of individual trials -- Meta-analysis model -- Estimation and hypothesis testing -- Testing for heterogeneity -- Exploration of heterogeneity -- Sensitivity analyses -- Presentation of results -- Estimating the treatment difference in an individual trial -- Binary data -- Example: Stroke in hypertensive patients -- Measurement of treatment difference -- Survival data -- Example: Mortality following myocardial infarction -- Measurement of treatment difference -- Interval-censored survival data -- Example: Ulcer recurrence -- Measurement of treatment difference -- Ordinal data -- Example: Global impression of change in Alzheimer's disease -- Measurement of treatment difference -- Normally distributed data -- Example: Recovery time after anaesthesia -- Measurement of treatment difference -- Combining estimates of a treatment difference across trials -- A general fixed effects parametric approach -- A fixed effects meta-analysis model -- Estimation and hypothesis testing of the treatment difference -- Testing for heterogeneity across studies -- Obtaining the statistics via weighted least-squares regression.
  note: Anne Whitehead.
  note: Includes bibliographical references (pages 321-328) and index.
  note: English.
  subject:
    topic: Clinical trials
    topic: Statistical methods
  subject:
    topic: Meta-analysis
  subject:
    topic: Controlled Clinical Trials
    topic: statistics & numerical data
  subject:
    topic: Meta-Analysis
  classification: R853.C55 W465 2002eb
  classification: 610/.7/27
  classification: WA 950 W592m 2002
  related item:
    title info:
      title: Meta-analysis of controlled clinical trials
    name:
      name part: Whitehead, Anne.
    origin info:
      publisher: Chichester ; New York : John Wiley & Sons, ©2002
    identifier: (DLC) 2002072173
  related item:
    title info:
      title: Statistics in practice (Chichester, England)
  identifier: 0470854197
  identifier: 9780470854198
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  identifier: 9780471983705
  identifier: 0471983705
  identifier: OverDrive, Inc.
  identifier: 47F42FFB-5247-4CBF-9841-0B682CC464E8 OverDrive, Inc.
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: NhCcYBP
    record creation date: 021119
    record change date: 20260214214552.2
    record identifier: in00004678271
    language of cataloging:
      language term: eng