http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
from in vivo and in vitro models to health risks
Nanotechnology is a rapidly developing, emerging branch of modern technology.
This new technology deals with materials of extremely small size, generally in the range of nanometres.
The nanomaterials, with their extremely small size and high surface area associated with greater strength, stability, chemical and biological activity, find their wide range of applications in a variety of products in modern society.
They are used in rapidly increasing nanoproducts, nanodevices, electronics, diagnostics and drug delivery systems.
They are present in a variety of consumer products such as foods, drugs, cosmetics, food colour additives, food containers, paints and surface coatings.
This trend is expected to result in an ever-increasing presence of nanoparticles in the human environment.
Because of their extremely small size they are capable of entering the human body by inhalation, ingestion, skin penetration, intravenous injections and medical devices, and have the potential to interact with intracellular macromolecules.
Because of their greater stability they are anticipated to remain in the body and in the environment for long periods of time.
However, information on their potential adverse health effects is very limited at the present time.
It is not known at what concentration or size they can exhibit toxicity.
Therefore, there are obvious public safety concerns.
This has led to the initiation of a new research discipline commonly known as nanotoxicology.
1. Characterization of nanomaterials for toxicological evaluation / Kevin W. Powers, Maria Palazuelos, Scott C. Brown and Stephen M. Roberts -- 2. Criteria and implementation of physical and chemical characteristics of nanomaterials for human health effects and ecological toxicity studies / Christie M. Sayes and David B. Warheit -- 3. Considerations for the design of toxicity studies of inhaled nanomedicines / Lea Ann Dailey -- 4. High aspect ratio nanoparticles and the fibre pathogenicity paradigm / Craig A. Poland, Rodger Duffin and Ken Donaldson -- 5. Application of zinc oxide quantum dots in food safety / Tony Jin, Dazhi Sun, Howard Zhang and Hung-Jue Sue -- 6. Evaluation of nanotoxicity of foods and drugs: biological properties of red elemental selenium at nano size (nano-se) in vitro and in vivo / Jinsong Zhang -- 7. Evaluation of toxicity of nanostructures in biological systems / Adam J. Gormley and Hamidreza Ghandehari -- 8. Developing bioassay methods for evaluating pulmonary hazards from nanoscale or fine quartz/titanium dioxide particulate materials / David B. Warheit, Kenneth L. Reed and Christie M. Sayes -- 9. Nanoparticles: is neurotoxicity a concern? / Jianyong Wang, Wenjun Sun and Syed F. Ali -- 10. Hepatoxic potential of nanomaterials / Saura C. Sahu -- 11. Nanotoxicity in blood: effects of engineered nanomaterials on platelets / Jan Simak -- 12. Sources, fate and effects of engineered nanomaterials in the aquatic environment / David S. Barber, Nancy D. Denslow, R. Joseph Griffitt and Christopher J. Martyniuk -- 13. Nanotoxicity of metal oxide nanoparticles in vivo / Weiyue Feng, Bing Wang and Yuliang Zhao.
14. In vivo hypersensitive pulmonary disease models for nanotoxicity / Ken-ichiro Inoue and Hirohisa Takano -- 15. In vivo and in vitro models for nanotoxicology testing / Rosalba Gornati, Elena Papis, Mario Di Gioacchino, Enrico Sabbioni, Isabella Dalle Donne, Aldo Milzani and Giovanni Bernardini -- 16. In vitro and in vivo toxicity study of nanoparticles / Jayoung Jeong, Wan-Seob Cho, Seung Hee Kim and Myung-Haing Cho -- 17. In vitro and in vivo models for nanotoxicity testing / Kyung O. Yu, Laura K. Braydich-Stolle, David M. Mattie, John J. Schlager and Saber M. Hussain -- 18. In vitro models for nanotoxicity testing / Yinfa Ma -- 19. In vitro human lung cell culture models to study the toxic potential of nanopartices / Fabian Blank, Peter Gehr and Barbara Rothen-Rutishauser -- 20. Iron oxide magnetic nanoparticle nanotoxicity: incidence and mechanisms / Thomas R. Pisanic, Sungho Jin and Veronica I. Shubayev -- 21. Toxicity testing and evaluation of nanoparticles: challenges in risk assessment / Daivd Y. Lai and Philip G. Sayre -- 22. Evaluating strategies for risk assessment of nanomaterials / Nastassja Lewinski, Huiguang Zhu and Rebekah Drezek -- 23. Strategies for risk assessment of nanomaterials / Hae-seong Yoon, Hyan-Kyung Kim, Dong Deuk Jang and Myung-Haing Cho -- 24. Metal nanoparticle health risk assessment / Mario Di Gioacchino, Nicola Verna, Rosalba Gornati, Enrico Sabbioni and Giovanni Bernardini -- 25. Application of toxicology studies in assessing the health risks of nanomaterials in consumer products / Joyce S. Tsuji, Fionna S. Mowat, Suresh Dontlu and Maureen Reitman -- 26. Safety assessment of engineered nanomaterials in direct food additives and food contact materials / Penelope A. Rice, Kimberly S. Cassidy, Jeremy Mihalov and T. Scott Thurmond.
editors, Saura C. Sahu and Daniel Casciano.
Includes bibliographical references and index.
Chichester, West Sussex, UK : John Wiley, 2009