BACE : Lead Target for Orchestrated Therapy of Alzheimer's Disease /

BACE inhibitors and their use in the treatment of Alzheimer's Disease. BACE (ß-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated The...

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Bibliographic Details
Other Authors:	John, Varghese, 1958-
Format:	eBook
Language:	English
Published:	Hoboken, N.J. : John Wiley & Sons, ©2010.
Subjects:	Alzheimer's disease > Chemotherapy. Aspartic proteinases > Inhibitors > Therapeutic use. Amyloid beta-protein precursor. Alzheimer Disease > drug therapy. Amyloid Precursor Protein Secretases > pharmacology. Amyloid Precursor Protein Secretases > therapeutic use. Electronic books.
Online Access:	Connect to the full text of this electronic book

Description
Summary:	BACE inhibitors and their use in the treatment of Alzheimer's Disease. BACE (ß-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery. This book details the story of the discovery of BACE and.
Physical Description:	1 online resource (1 electronic resource (xvi, 250 pages, 16 unnumbered pages of plates)) : illustrations (some color)
Bibliography:	Includes bibliographical references and index.
ISBN:	9780470594087 047059408X 9780470594070 0470594071 128249175X 9781282491755 047029342X 9780470293423