Transporters as drug targets /
As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacolog...
| Other Authors: | , , |
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| Format: | eBook |
| Language: | English |
| Published: |
Weinheim, Germany :
Wiley-VCH,
[2017]
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| Series: | Methods and principles in medicinal chemistry ;
v. 70. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease. |
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| Physical Description: | 1 online resource (xviii, 335 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783527679515 3527679510 9783527679522 3527679529 9783527679539 3527679537 9783527679430 352767943X |