Kinomics : approaches and applications /
Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kino...
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| Format: | eBook |
| Language: | English |
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Weinheim [Germany] :
Wiley-VCH,
[2015]
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Part I: Protein Kinases Cell Signaling. Global Approaches to Understanding Protein Kinase Functions / Jennifer L Gorman, James R Woodgett
- Genuine Casein Kinase (Fam20C): The Mother of the Phosphosecretome / Giorgio Cozza, Vincent S Tagliabracci, Jack E Dixon, Lorenzo A Pinna
- Chemical Biology of Protein Kinases / David Mann
- Protein Kinases and Caspases: Bidirectional Interactions in Apoptosis / Stephanie A Zukowski, David W Litchfield
- The Kinomics of Malaria / Mathieu Brochet, Andrew B Tobin, Oliver Billker, Christian Doerig
- Part II: ATP Co-substrate Design. ATP Analogs in Protein Kinase Research / Thilani M Anthony, Pavithra M Dedigama-Arachchige, D Maheeka Embogama, Todd R Faner, Ahmed E Fouda, Mary Kay H Pflum
- Electrochemical Detection of Protein Kinase-Catalyzed Phosphorylations / Sanela Martic, Soha Ahmadi, Zhe She, Heinz-Bernhard Kraatz
- Part III: New Methodologies for Kinomics. Phos-tag Technology for Kinomics / Emiko Kinoshita-Kikuta, Eiji Kinoshita, Tohru Koike
- Development of Species- and Process-Specific Peptide Kinome Arrays with Priority Application to Investigations of Infectious Disease / Ryan Arsenault, Brett Trost, Anthony Kusalik, Scott Napper
- New Approaches to Understanding Bacterial Histidine Kinase Activity and Inhibition / Kaelyn E Wilke, Erin E Carlson
- Methods for Large-Scale Identification of Protein Kinase Substrate Networks / KassaDee J Ketelaar, Ian S Wallace
- Part IV: Kinase Inhibition. Developing Inhibitors of STAT3: Targeting Downstream of the Kinases for Treating Disease / Andrew M Lewis, Daniel P Ball, Rahul Rana, Ji Sung Park, David Rosa, Ping-Shan Lai, Rodolfo F Gómez-Biagi, Patrick T Gunning
- Metal Compounds as Kinase and Phosphatase Inhibitors in Drug Development: The Role of the Metal and Ligands / Maria V Babak, Margaux Airey, Christian G Hartinger.