Kinomics : approaches and applications /
Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kino...
| Other Authors: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Weinheim [Germany] :
Wiley-VCH,
[2015]
|
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown. The result is a toolbox for every kinase. |
|---|---|
| Physical Description: | 1 online resource |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783527683031 3527683038 9783527683048 3527683046 9783527683055 3527683054 9783527683062 3527683062 |