Long-lived proteins in human aging and disease /

"While most proteins in the human body are short-lived and are constantly being regenerated, this is not true for all. A significant fraction of proteins in long-lived cells such as nerve cells are likewise long-lived and will age over time by accumulating damage and other modifications. Scient...

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Bibliographic Details
Other Authors: Truscott, Roger J. W. (Editor)
Format: eBook
Language:English
Published: Weinheim, Germany : Wiley-VCH GmbH, [2021]
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Introduction to the Book
  • Long-Lived Cells and Long-Lived Proteins in the Human Body / Roger JW Truscott
  • Imaging Mass Spectrometry of Long-Lived Proteins / Kevin L Schey
  • Eye Lens Crystallins: Remarkable Long-Lived Proteins / Aidan B Grosas, John A Carver
  • Spontaneous Breakdown of Long-Lived Proteins in Aging and Their Implications in Disease / Michael G Friedrich
  • Modifications of Long-Lived Proteins that Affect Protein Solubility / Larry L David
  • Degradation of Long-Lived Proteins as a Cause of Autoimmune Diseases / Roger JW Truscott
  • How Isomerization and Epimerization in Long-Lived Proteins Affect Lysosomal Degradation and Proteostasis / Ryan R Julian
  • The Maillard Reaction: Protein Modification by Ascorbic Acid / Vincent M Monnier, David R Sell, Grant Hom, Shiyuan Dong, Benlian Wang, Xingjun Fan.