rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Structure-based design of drugs and other bioactive molecules
    sub title: tools and strategies
  name:
    name part: Ghosh, Arun K.
    name part: Prof. Dr
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: Gemma, Sandra
    role:
      role term: author.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: gw
    date issued: 2014
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource (xv, 458 pages : : illustrations.)
  table of contents: 1. From Traditional Medicine to Modern Drugs: Historical Perspective of Structure-Based Drug Design -- Part One Concepts, Tools, Ligands, and Scaffolds for Structure-Based Design of Inhibitors -- 2. Design of Inhibitors of Aspartic Acid Proteases -- 3. Design of Serine Protease Inhibitors -- 4. Design of Proteasome Inhibitors -- 5. Design of Cysteine Protease Inhibitors -- 6. Design of Metalloprotease Inhibitors -- 7. Structure-Based Design of Protein Kinase Inhibitors -- 8. Protein X-Ray Crystallography in Structure-Based Drug Design -- 9. Structure-Based Design Strategies for Targeting G-Protein-Coupled Receptors (GPCRs) -- Part Two Structure-Based Design of FDA-Approved Inhibitor Drugs and Drugs Undergoing Clinical Development -- 10. Angiotensin-Converting Enzyme Inhibitors for the Treatment of Hypertension: Design and Discovery of Captopril.
  table of contents: 11. HIV-1 Protease Inhibitors for the Treatment of HIV Infection and AIDS: Design of Saquinavir, Indinavir, and Darunavir -- 12. Protein Kinase Inhibitor Drugs for Targeted Cancer Therapy: Design and Discovery of Imatinib, Nilotinib, Bafetinib, and Dasatinib -- 13. NS3/4A Serine Protease Inhibitors for the Treatment of HCV: Design and Discovery of Boceprevir and Telaprevir -- 14. Proteasome Inhibitors for the Treatment of Relapsed Multiple Myeloma: Design and Discovery of Bortezomib and Carfilzomib -- 15. Development of Direct Thrombin Inhibitor, Dabigatran Etexilate, as an Anticoagulant Drug -- 16. Non-Nucleoside HIV Reverse Transcriptase Inhibitors for the Treatment of HIV/AIDS: Design and Development of Etravirine and Rilpivirine -- 17. Renin Inhibitor for the Treatment of Hypertension: Design and Discovery of Aliskiren -- 18. Neuraminidase Inhibitors for the Treatment of Influenza: Design and Discovery of Zanamivir and Oseltamivir -- 19. Carbonic Anhydrase Inhibitors for the Treatment of Glaucoma: Design and Discovery of Dorzolamide -- 20 B-Secretase Inhibitors for the Treatment of Alzheimer's Disease: Preclinical and Clinical Inhibitors.
  note: Arun K. Ghosh and Sandra Gemma.
  note: Includes bibliographical references and index.
  subject:
    topic: Drug development
  subject:
    topic: Bioactive compounds
  subject:
    topic: Biopolymers
  subject:
    topic: Ligand binding (Biochemistry)
  subject:
    topic: Protease inhibitors
  subject:
    topic: Drugs
    topic: Structure-activity relationships
  subject:
    topic: Drugs
    topic: Design
  subject:
    topic: Molecular structure
  subject:
    topic: Structure-activity relationships (Biochemistry)
  subject:
    topic: Drug Design
  subject:
    topic: Molecular Structure
  subject:
    topic: Biopolymers
    topic: chemistry
  subject:
    topic: Protease Inhibitors
    topic: chemistry
  subject:
    topic: Structure-Activity Relationship
  subject:
    topic: Biopolymers
  classification: RS403
  classification: 615.19
  classification: 2014 I-322
  classification: QV 745
  related item:
    identifier: (GyWOH)har145013411
  related item:
    identifier: (GyWOH)har145013413
  related item:
    identifier: (GyWOH)har145013414
  identifier: 9783527665211 (electronic bk.)
  identifier: 3527665218 (electronic bk.)
  identifier: 9783527333653
  identifier: 3527333657
  identifier: http://proxy.library.tamu.edu/login
  record info:
    record content source: NhCcYBP
    record creation date: 230502
    record change date: 20260214211755.3
    record identifier: in00004675368
    language of cataloging:
      language term: eng