Antibiotics : targets, mechanisms and resistance /
"Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Openin...
| Other Authors: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Weinheim, Germany :
Wiley-VCH,
©2014.
|
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Summary: | "Most of the antibiotics now in use have been discovered more or less by chance, and their mechanisms of action have only been elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly needed. Opening with a general introduction about antimicrobial drugs, their targets and the problem of antibiotic resistance, this reference systematically covers currently known antibiotic classes, their molecular mechanisms and the targets on which they act. Novel targets such as cell signaling networks, riboswitches and bacterial chaperones are covered here, alongside the latest information on the molecular mechanisms of current blockbuster antibiotics. With its broad overview of current and future antibacterial drug development, this unique reference is essential reading for anyone involved in the development and therapeutic application of novel antibiotics"--EBL. |
|---|---|
| Physical Description: | 1 online resource (xxiv, 549 pages) : illustrations (some color) |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783527659685 3527659684 1299854656 9781299854659 9783527659715 3527659714 9783527333059 3527333053 9783527659708 3527659706 9783527659692 3527659692 |