Correlative light and electron microscopy IV /

Abstract: Correlative light and electron microscopy (CLEM) combines the strengths of light microscopy (LM) and electron microscopy (EM) to pin-point and visualize cellular or macromolecular structures. However, there are many different imaging modalities that can be combined in a CLEM workflow, crea...

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Bibliographic Details
Corporate Author: ScienceDirect (Online service)
Other Authors: Müller-Reichert, Thomas, Verkade, Paul
Format: eBook
Language:English
Published: Cambridge, MA : Academic Press, 2021.
Series:Methods in cell biology ; v. 162.
Subjects:
Online Access:Connect to the full text of this electronic book
Description
Summary:Abstract: Correlative light and electron microscopy (CLEM) combines the strengths of light microscopy (LM) and electron microscopy (EM) to pin-point and visualize cellular or macromolecular structures. However, there are many different imaging modalities that can be combined in a CLEM workflow, creating a vast number of combinations that can overwhelm new-comers to the field. Here, we offer a conceptual framework to help guide the decision-making process for choosing the CLEM workflow that can best address your research question, based on the answer to five questions.
Physical Description:1 online resource
ISBN:9780128220597
0128220597