Introduction to bioinformatics /
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| Corporate Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Boca Raton :
Chapman and Hall/CRC,
2018.
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| Edition: | 1st |
| Series: | Chapman & Hall/CRC mathematical and computational biology
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| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
| Item Description: | Previously issued in print: 2007. <B> The Data: Storage and Retrieval</b> <br>Basic Principles <br>The Data <br>Data Quality <br>Data Representation <br><b>Genome Sequence Analysis</b> <br>Basic Concepts <br>Genome Sequencing <br>Finding the Genes <br>Statistical Methods to Search for Genes <br>Comparative Genomics <br>A Virtual Window on Genomes: The World Wide Web <br><b>Protein Evolution</b> <br>Basic Concepts <br>Molecular Evolution <br>How to Align Two Similar Sequences <br>Similarity Matrices <br>Penalties for Insertions and Deletions <br>The Alignment Algorithm <br>Multiple Alignments <br>Phylogenetic Trees <br><b>Similarity Searches in Databases</b> <br>Basic Principles <br>The Methods <br><b>Amino Acid Sequence Analysis</b> <br>Basic Principles <br>Search for Sequence Patterns <br>Feature Extraction <br>Secondary Structure: Part One <br><b>Prediction of the Three-Dimensional Structure of a Protein </b> <br>Basic Principles <br>The CASP Experiment <br>Secondary Structure Prediction: Part Two <br>Long-Range Contact Prediction <br>Predicting Molecular Complexes: Docking Methods <br><b>Homology Modeling</b> <br>Basic Principles <br>The Steps of Comparative Modeling <br>Accuracy of Homology Models <br>Manual versus Automatic Models <br>Practical Notes <br>Summing Up <br><b>Fold Recognition Methods</b> <br>Basic Principles <br>Profile-Based Methods <br>Threading Methods <br>The Fold Library <br>How Well Do These Methods Work? <br><b>New Fold Modeling</b> <br>Basic Principles <br>Estimating the Energy of a Protein Conformation <br>Energy Minimization <br>Molecular Dynamics <br><b>The "Omics" Universe</b> <br>Basic Principles <br>Transcriptomics <br>Proteomics <br>Interactomics <br>Structural Genomics <br>Pharmacogenomics <br>But This Is Not All <br><b>Useful Web Sites </b> <br><b>Index</b> <br><i>A Glossary, References, and Problems appear in each chapter.</i> |
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| Physical Description: | 1 online resource : illustrations (black and white, and colour) |
| ISBN: | 9781351989411 1351989413 9781420010886 1420010883 9781466527096 1466527099 9781315276014 1315276011 |