Successful drug discovery. Volume 5 /

Bibliographic Details
Other Authors: Fischer, János (Editor), Klein, Christian (Editor), Childers, Wayne E. (Editor)
Format: eBook
Language:English
Published: Weinheim, Germany : Wiley-VCH, [2021]
Subjects:
Online Access:Connect to the full text of this electronic book.
Table of Contents:
  • Drug discovery in academia
  • From degraders to molecular glues : new ways of breaking down disease-associated proteins
  • GLP-1 receptor agonists for the treatment of type 2 diabetes and obesity
  • Recent advances on SGLT2 inhibitors : synthetic approaches, therapeutic benefits, and adverse events
  • CAR T cells : a novel biological drug class
  • CGRP inhibitors for the treatment of migraine
  • Discovery and development of Emicizumab (HEMLIBRA) : a humanized bispecific antibody to coagulation factors IXa and X with a factor VIII cofactor activity
  • Discovery and development of Ivosidenib (AG-120 : TIBSOVO)
  • The discovery of Kisqali (Ribociclib) : a CDK4/6 inhibitor for the treatment of HR+/HER2- advanced breast cancer.