Chemistry of protein and nucleic acid cross-linking and conjugation /
"Since the publication of the first edition of Chemistry of Protein Conjugation and Cross-Linking in 1991, new cross-linking reagents, notably multifunctional cross-linkers, have been developed and synthesized. The completion of the human genome project has opened a new area for studying nuclei...
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| Format: | eBook |
| Language: | English |
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Boca Raton :
CRC Press,
2012.
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| Edition: | Second edition. |
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| Online Access: | Connect to the full text of this electronic book. |
Table of Contents:
- Overview of protein conjugation
- Review of protein and nucleic acid chemistry
- Reagents targeted to specific functional groups
- How to design and choose cross-linking reagents
- Homobifunctional cross-linking reagents
- Heterobifunctional cross-linkers
- Multifunctional cross-linking reagents
- Monofunctional and zero-length cross-linking reagents
- General approaches for chemical cross-linking
- Analysis of cross-linked products
- Applications of chemical cross-linking to the study of biological macromolecules
- Applications of chemical conjugation in the preparation of immunoconjugates and immunogens
- Application of chemical conjugation for the preparation of immunotoxins and other drug conjugates for targeting theraputics
- Application of chemical conjugation to solid-state chemistry.