http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
1 online resource : illustrations (some color)
Overview of DNA repair pathways -- Longevity assurance by genome maintenance -- Genetic instability of cancer : biological predictions and clinical implications -- Radiation induced DNA damage, repair, and therapeutics -- Chemotherapeutic alkylating agents in cancer treatment -- O6-methylguanine-DNA methyltransferase (MGMT) in cancer protection and therapy -- DNA mismatch repair : it's role in human carcinogenesis and as a predictive and/or prognostic biomarker for cancer therapy -- DNA base excision repair therapeutics : summary of targets with a focus on APE1 -- Nucleotide excision repair : DNA repair capacity variability and cancer susceptibility -- Fanconi anemia, interstrand cross-link repair, and cancer -- Functions of translesion DNA polymerases : implications for cancer risk and opportunities as therapeutic targets -- P53 in DNA damage, repair and cancer therapeutics -- ATM/ATR cell cycle checkpoints : mechanisms and manipulation in cancer therapy -- The BRCA1-BRCA2 pathway of homologous recombination and the opportunity for synthetic lethal approaches to cancer therapy -- PARP and PARP inhibitor therapeutics -- Tumor genetics and personalized medicine -- The tumor microenvironment and DNA repair : implications for cancer progression and treatment -- Early phase clinical trials using DNA repair inhibitors : lessons learnt.
editors, Srinivasan Madhusudan, David M. Wilson III.
Description based on opening page (viewed Jan 02, 2018).