http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
xviii, 702 pages, 24 unnumbered pages of plates : illustrations ; 26 cm.
"MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics.Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research"--Provided by publisher.
MicroRNAs: a brief introduction -- MicroRNA regulation of stem cell fate and reprogramming -- MicroRNAs as regulators of immunity -- Regulation of senescence by microRNAs -- The emergence of geroMIRS: a group of microRNAs implicated in aging -- MicroRNAs and hematopoiesis -- MicroRNAs in platelet production and activation -- MicroRNAs as key players in host-virus interactions -- MicroRNA expression in avian herpesviruses -- Function of human cytomegalovirus microRNAs and potential roles in latency -- Involvement of small non-coding RNA in HIV-1 infection -- MicroRNA in malaria
The microRNA decalog of cancer involvement -- MicroRNAs as oncogenes and tumor suppressors -- Long non-coding RNAs and their roles in cancer -- Regulation of hypoxia responses by microRNA expression -- Control of receptor function by microRNAs in breast cancer -- MicroRNAs in human prostate cancer: from pathogenesis to therapeutic implications -- MicroRNA signatures as biomarkers of colorectal cancer -- Genetic variations in microRNA-encoding sequences and microRNA target sites alter lung cancer susceptibility and survival -- MicroRNAs in myelopoiesis and myeloid disorders -- MicroRNA deregulation by aberrant DNA methylation in acute lymphoblastic leukemia -- Role of miRNAs in the pathogenesis of chronic lymphocytic leukemia -- MicroRNA in B-cell non-Hodgkin lymphoma: Diagnostic markers and therapeutic targets -- MicroRNAs in diffuse large B-cell lymphoma -- The role of microRNAs in Hodgkin lymphoma -- MicroRNA expression in cutaneous T-cell lymphomas
MicroRNAs and hereditary disorders -- MicroRNAs and cardiovascular diseases -- MicroRNAs and diabetes -- MicroRNAs in liver disease -- MicroRNA regulation in multiple sclerosis -- The role of microRNAs in Alzheimer's disease -- Current views on the role microRNAs in psychosis -- Circulating microRNAs as non-invasive biomarkers -- Circulating microRNAs as cellular messengers -- Release of microRNA-containing vesicles can stimulate angiogenesis and metastasis in renal carcinoma -- MicroRNA regulation of cancer stem cells and microRNAs as potential cancer stem cell therapeutics -- Therapeutic modulation of microRNAs -- Silencing of MicroRNA-122 in primates with chronic hepatitis C virus infection
Includes bibliographical references and index.