P53 in the clinics /

Bibliographic Details
Other Authors: Hainaut, Pierre, Olivier, Magali, Wiman, Klas
Format: eBook
Language:English
Published: New York : Springer, [2013]
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • TP53: coordinator of the processes that underlie the hallmarks of cancer
  • The inheritance of p53
  • p53: guardian of the metabolome
  • The p53 family and stem cell biology
  • Mutant p53-driven tumorigenesis
  • Humanised mouse models: targeting the murine p53 locus with human sequences
  • p53 models for mammary carcinogenesis
  • TP53 somatic mutations: prognostic and predictive value in human cancers
  • Assessing TP53 status in human tumors: lessons from breast cancer
  • TP53 germline mutations: genetics of li-fraumeni syndrome
  • Tp53 gene therapy for cancer treatment and prevention
  • Upstream targets in the p53 pathway
  • p53-reactivating molecules as research tools and anticancer drugs
  • Targeting mutant p53 for improved cancer therapy
  • p53 immunotherapy of cancer
  • Designing p53 trials: a surgical oncologists view
  • p53 in the clinic: a pathologist's view
  • Genetic counseling for TP53 germline mutations