Brain diseases and metalloproteins /

Bibliographic Details
Other Authors: Brown, David R. (David Ronald), 1964-
Format: eBook
Language:English
Published: Boca Raton, FL : Pan Stanford Publishing : CRC Press, [2012]
Subjects:
Online Access:Connect to the full text of this electronic book.
Table of Contents:
  • Introduction
  • A possible key role for redox-active metal ions and soluble oligomers in neurodegenerative disease
  • Modelling of the metal binding sites in proteins involved in neurodegeneration
  • Mammalian metallothioneins
  • Copper transporting P-type ATPases in the brain
  • Role of the amyloid precursor protein and copper in Alzheimer's disease
  • Role of aluminum and other metal ions in the pathogenesis of Alzheimer's disease
  • Prion diseases, metals and antioxidants
  • Emerging role for copper-bound [alpa]-synuclein in Parkinson's disease etiology
  • Interactions of [alpha]-synuclein with metal ions : new insights into the structural biology and bioinorganic chemistry of Parkinson's disease
  • An attempt to treat amyotrophic lateral sclerosis by intracellular copper modification using ammonium tetrathiomolybdate and/or metallothionein : fundamentals and perspective.