Handbook of ELISPOT : methods and protocols /

Bibliographic Details
Other Authors: Kalyuzhny, Alexander E. (Editor)
Format: Book
Language:English
Published: New York : Humana Press, 2018.
Edition:Third edition.
Series:Methods in molecular biology (Clifton, N.J.) ; v. 1808.
Springer protocols (Series)
Subjects:
Table of Contents:
  • Challenges in developing protein secretion assays at a single-cell level
  • Mastering the computational challenges of Elispot plate evaluation
  • Essential controls for ELISpot assay
  • Automatic search of spots and color classification in ELISPOT assay
  • Four color ImmunoSpot assays for identification of effector T-cell lineages
  • Detection of cross-reactive B cells using the FluoroSpot assay
  • Multiplex ImmunoSpot assays for the study of functional B cell subpopulations
  • Detecting all immunoglobulin classes and subclasses in a multiplex 7 color ImmunoSpot assay
  • Multiplexing T- and B-cell FLUOROSPOT assays : experimental validation of the multi-color ImmunoSpot software based on center of mass distance algorithm
  • Multi-color FLUOROSPOT counting using ImmunoSpot Fluoro-X suite
  • B-Cell ELISpot assay to quantify antigen-specific antibody-secreting cells in human peripheral blood mononuclear cells
  • Identification of novel mycobacterial targets for murine CD4+ T-cells by IFNγ ELISPOT
  • ELISPOT-based "Multi-Color FluoroSpot" to study type-specific and cross-reactive responses in memory B cells after Dengue and Zika virus infections
  • Cultured ELISpot assay to investigate Dengue virus specific T-cell responses
  • Ex vivo ELISpot assay to investigate Dengue virus specific T-cell responses
  • Ex vivo ELISpot assay to investigate iNKT cell responses in acute Dengue infection
  • Dendritic cell-based ELISpot assay for assessing T-cell IFN-γ responses in human peripheral blood mononuclear cells in Dengue envelope proteins
  • Utilization of feline ELISpot to evaluate the immunogenicity of a T cell-based FIV MAP vaccine
  • Detection and quantification of influenza A/H1N1 virus-speceifc memory B cells in human PBMCs using ELISpot assay
  • Towards a full automation of the ELISpot assay for safe and parallelized immunomonitoring.