Comparative pharmacokinetics /
"Now in a newly revised edition, Comparative Pharmacokinetics presents the principles and techniques of pharmacokinetics in a detailed, yet practical and easily understandable manner. Coverage includes an overview of the basic physiologic processes of drug absorption and disposition and detaile...
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| Format: | eBook |
| Language: | English |
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Chichester, West Sussex :
Wiley-Blackwell,
2011.
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| Edition: | Second edition. |
| Subjects: | |
| Online Access: | Connect to the full text of this electronic book |
Table of Contents:
- Introduction
- Principles of drug movement in the body
- Quantitative structure--permeability relationships
- Absorption
- Distribution
- Renal elimination
- Hepatic biotransformation and biliary excretion
- Compartmental models
- Noncompartmental models
- Nonlinear models
- Physiological models
- Dosage regimens
- Simultaneous pharmacokinetic--pharmacodynamic modeling
- Study design and data analysis
- Bioequivalence studies-- Population pharmacokinetic models
- Dosage adjustments in disease states
- Interspecies extrapolations
- Tissue residues and withdrawal times