Comparative pharmacokinetics /

"Now in a newly revised edition, Comparative Pharmacokinetics presents the principles and techniques of pharmacokinetics in a detailed, yet practical and easily understandable manner. Coverage includes an overview of the basic physiologic processes of drug absorption and disposition and detaile...

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Bibliographic Details
Main Author: Riviere, J. Edmond (Jim Edmond) (Author)
Corporate Author: Wiley InterScience (Online service)
Format: eBook
Language:English
Published: Chichester, West Sussex : Wiley-Blackwell, 2011.
Edition:Second edition.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Introduction
  • Principles of drug movement in the body
  • Quantitative structure--permeability relationships
  • Absorption
  • Distribution
  • Renal elimination
  • Hepatic biotransformation and biliary excretion
  • Compartmental models
  • Noncompartmental models
  • Nonlinear models
  • Physiological models
  • Dosage regimens
  • Simultaneous pharmacokinetic--pharmacodynamic modeling
  • Study design and data analysis
  • Bioequivalence studies-- Population pharmacokinetic models
  • Dosage adjustments in disease states
  • Interspecies extrapolations
  • Tissue residues and withdrawal times