Tuberculosis : laboratory diagnosis and treatment strategies /

Tuberculosis is a global health threat and the unique features of Mycobacterium tuberculosis and emergence of drug-resistant strains highlight the challenge it presents. Covering a wealth of state-of-the-art knowledge from active international experts, this book captures the latest developments in t...

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Bibliographic Details
Other Authors: McHugh, Timothy D. (Timothy Daniel) (Editor)
Format: eBook
Language:English
Published: Wallingford, Oxfordshire : CABI, [2013]
Series:Advances in molecular and cellular microbiology ; 21.
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Improving upon sputum smear microscopy for diagnosis of tuberculosis in resource-poor settings
  • Molecular diagnosis of active pulmonary tuberculosis
  • Improving on the LJ slope : automated liquid culture
  • Interferon-gamma release assays in the diagnosis of latent tuberculosis infection
  • Measuring tuberculosis immune responses in the lung : the correct target?
  • Sniffing out tuberculosis-- Role of phenotypic methods for drug susceptibility testing of M. tuberculosis isolates in the era of MDR and XDR epidemics
  • Genotypic measures of antibiotic susceptibility
  • Molecular tools for fast identification of resistance and characterization of MDR/XDR-TB
  • Monitoring therapy by bacterial load
  • Modelling responses to tuberculosis treatment
  • Measuring gene expression by quantitative PCR (qPCR)
  • Transcriptomic approaches to mapping responses to drug therapy for tuberculosis
  • Mycobacterial lipid bodies and resuscitation-promoting factor dependency as potential biomarkers of response to chemotherapy
  • Clinical trials in tuberculosis chemotherapy : the challenges
  • The identification of 2-aminothiazole-4-carboxylates (ATCs) as a new class of tuberculosis agent : a lesson in "HIT" identification
  • Rifamycins revisited
  • Therapy of the XDR-TB patient with thioridazine: an old drug with new applications
  • Vaccines for tuberculosis