rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Systems biology in drug discovery and development
  name:
    name part: Young, Daniel L.
    role:
      role term: editor.
  name:
    name part: Michelson, Seth
    role:
      role term: editor.
  type of resource: text
  genre: bibliography
  origin info:
    place:
      place term: nju
    date issued: 2012
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: xvii, 370 pages : illustrations (some color) ; 25 cm.
  table of contents: Introduction to systems biology in drug discovery and development -- Methods for in silico biology : model construction and analysis -- Methods in in silico biology : modeling feedback dynamics in pathways -- Simulation of population variability in pharmacokinetics -- Applications of systems biology approaches to target identification and validation in drug discovery -- Lead identification and optimization -- The role of core biological motifs in dose-response modeling : an example with switch-like circuits -- Mechanism based pharmacokinetic-pharmacodynamic modeling during discovery and early development -- Developing oncology drugs using virtual patients of vascular tumor diseases -- Systems modeling applied to candidate biomarker identification -- Simulating clinical trials -- Pathway analysis in drug discovery -- Functional mapping for predicting drug response and enabling personalized medicine -- Future outlook of systems biology.
  note: edited by Daniel L. Young, Seth Michelson.
  note: Includes bibliographical references and index.
  subject:
    topic: Drug development
  subject:
    topic: Systems biology
  subject:
    topic: Drug Discovery
    topic: methods
  subject:
    topic: Models, Biological
  subject:
    topic: Pharmacokinetics
  subject:
    topic: Pharmacological Processes
  subject:
    topic: Systems Biology
    topic: methods
  classification: RM301.25 .S97 2012
  classification: 615/.19
  classification: QV 744
  classification: QV 744 S995 2012
  related item:
    title info:
      title: Wiley series on technologies for the pharmaceutical industry
  identifier: 9780470261231 (cloth)
  identifier: 0470261234 (cloth)
  identifier: 2010043475
  record info:
    record content source: DNLM/DLC
    record creation date: 101013
    record change date: 20191204154007.0
    record identifier: in00004517571