rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    non sort: The
    title: COST manual of laboratory animal care and use
    sub title: refinement, reduction, and research
  name:
    name part: Howard, Bryan.
  name:
    name part: Nevalainen, Timo J.
  name:
    name part: Perretta, Gemma.
  name:
    name part: European Cooperation in the Field of Scientific and Technical Research (Organization)
  type of resource: text
  genre: bibliography
  genre: Laboratory Manuals.
  origin info:
    place:
      place term: flu
    date issued: 2011
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: print
    extent: xvii, 421 pages : illustrations ; 27 cm.
  abstract: "Our intention is to offer a one-stop source of best practice, which will be of value to personnel responsible for the care and welfare of animals and scientists conducting activities related to the use of animals for scientific purposes. It is also addressed to those with management responsibilities including facility engineers, architects and lay persons involved with ethical review, and the interested general reader. The manual presents perceived best practices and, as far as possible, the contents are evidence based. In the many cases / Summary: where the evidence is poor, the authors have endeavoured to demonstrate the rationale underlying their contentions by including relevant references. The emphasis is not on describing current practices, but rather what is seen as good practice; moreover it is not our intention to tell the reader what to do, but rather to offer options and provide advice on what not to do."--Provided by publisher.
  table of contents: Introduction -- Design and oversight of laboratory animal facilities -- Housing and care of laboratory animals -- Animal needs and environmental refinement -- Ethical evaluation of scientific procedures recommendations for ethics committees -- Reduction by careful design and statistical analysis -- Animal models : selecting and preparing animals for a study -- Creation of genetically modified animals -- Management of genetically modified rodents -- Impact of handling, radiotelemetry, and food restriction -- Basic procedures : dosing, sampling and immunisation -- Imaging techniques -- Anaesthesia and analgesia -- Use of humane endpoints to minimise suffering -- Euthanasia -- Education, training and competence -- Animal experimentation and open communication
  note: edited by Bryan Howard, Timo Nevalainen, Gemma Perretta.
  note: Includes bibliographical references and index.
  subject:
    topic: Laboratory animals
    genre: Laboratory manuals
  subject:
    topic: Animals, Laboratory
  subject:
    topic: Animal Welfare
  subject:
    topic: Laboratory Techniques and Procedures
    topic: veterinary
  classification: SF406 .C67 2011
  classification: 636.088/5
  classification: 2010 M-702
  classification: QY 25
  classification: QY 25 C837 2011
  identifier: 9781439824924 (hardcover : alk. paper)
  identifier: 1439824924 (hardcover : alk. paper)
  identifier: 2010032400
  record info:
    record content source: DNLM/DLC
    record creation date: 100729
    record change date: 20191204153812.0
    record identifier: in00004513874