Conjugation and deconjugation of ubiquitin family modifiers /

Bibliographic Details
Other Authors: Groettrup, Marcus, 1964-
Format: Book
Language:English
Published: Austin, Tex. : New York : Landes Bioscience ; Springer Science + Business Media, [2010]
Series:Sub-cellular biochemistry ; v. 54.
Subjects:
Table of Contents:
  • Activation of ubiquitin and ubiquitin-like proteins
  • Control of ubiquitin conjugation by CDC48 and its cofactors
  • Regulation of ubiquitin receptors by coupled monoubiquitination
  • Control of cullin-ring ubiquitin ligase activity by Nedd8
  • Control of deneddylation by the COP9 signalosome
  • Mechanism, specificity, and structure of the deubiquitinases
  • Ubiquitin conjugation and deconjugation in Nf-kB signaling
  • Functions of linear ubiquitin chains in the Nf-kB pathway : linear polyubiquitin in Nf-kB signaling
  • Assembly of K11-linked ubiquitin chains by the anaphase promoting complex
  • Ubiquitin family members in the regulation of the tumor suppressor p53
  • Ubiquitylation in the ERAD pathway
  • Pupylation : a signal for proteasomal degradation in mycobacterium tuberculosis
  • SUMO control
  • The in vivo functions of desumoylating enzymes
  • Regulatory functions of ubiquitin and SUMO in DNA repair pathways
  • Sumoylation as a signal for polyubiquitylation and proteasomal degradation
  • In vivo functions of isgylation
  • Identification and validation of ISG15 target proteins
  • FAT10 : activated by UBA6 and functioning in protein degradation