TNF pathophysiology : molecular and cellular mechanisms /

Bibliographic Details
Other Authors:	Kollias, G. (George), Sfikakis, P. P. (Petros P.)
Format:	Book
Language:	English
Published:	Basel, Switzerland ; New York : Karger, [2010]
Series:	Current directions in autoimmunity ; v. 11.
Subjects:	Tumor necrosis factor > Pathophysiology. Tumor Necrosis Factors > immunology. Tumor Necrosis Factors > physiology. Transcription, Genetic > immunology.

Table of Contents:

Cellular mechanisms of TNF function in models of inflammation and autoimmunity
Transcriptional control of the TNF gene
Posttranscriptional regulation of TNF mRNA : a paradigm of signal-dependent mRNA utilization and its relevance to pathology
Role of TNF in pathologies induced by nuclear factor kB deficiency
Type I interferon : a new player in TNF signaling
T cells as sources and targets of TNF : implications for immunity and autoimmunity
TNF-a : an activator of CD4+FoxP3+TNFR2+regulatory T cells
TNF and bone
TNF-a and obesity
TNF in host resistance to tuberculosis infection
The first decade of biologic TNF antagonists in clinical practice : lessons learned, unresolved issues and future directions