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Structure and function of intrinscially disordered proteins /

Bibliographic Details
Main Author: Tompa, Peter
Format: Book
Language:English
Published: Boca Raton : CRC Press/Chapman & Hall, [2010]
Subjects:
Proteins > Pathophysiology.
Proteins > Structure-activity relationships.
Proteins > Metabolism > Disorders.
Protein Conformation.
Protein Denaturation.
Protein Folding.
Structure-Activity Relationship.
Table of Contents:
  • Principles of protein structure and function
  • A brief history of protein disorder
  • Indirect techniques for recognizing and characterizing protein disorder
  • Hydrodynamic techniques
  • Spectroscopic techniques for characterizing disorder
  • Nuclear magnetic resonance
  • Proteomic approaches for the identification of IDPs
  • IDPs under conditions approaching in vivo
  • Prediction of disorder
  • Structure of IDPs
  • Biological processes enriched in disorder
  • Molecular functions of disordered proteins
  • Evolution and prevalence of disorder
  • Extension of the structure-function paradigm
  • Structural disorder and disease.