RNA polymerases as molecular motors /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge, U.K. :
RSC Pub.,
[2009]
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| Series: | RSC biomolecular sciences.
|
| Subjects: |
Table of Contents:
- There and back again: a structural atlas of RNAP
- Part I from promoter recognition to promoter escape
- Where it all begins: an overview of promoter recognition and open complex formation
- Opening the DNA at the promoter; the energetic challenge
- Intrinsic in vivo modulators: negative supercoiling and the constituents of the bacterial nucleoid
- Transcription by RNA polymerases: from initiation to elongation, translocation and strand separation
- Single-molecule FRET analysis of the path from transcription initiation to elongation
- Real-time detection of DNA unwinding by Escherichis coli RNAP: from transcription initiation to termination
- Part II transcription elongation and termination
- Interlude the engine and the brake
- Substrate loading, nucleotide addition, and translocation by RNA polymerase
- Regulation of RNA polymerase through its active center
- Kinetic modeling of transcription elongation
- Mechanics of transcription termination
- Conclusion past, present, and future of single-molecule studies of transcription.