Recombinant antibodies for immunotherapy /
| Other Authors: | |
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| Format: | Book |
| Language: | English |
| Published: |
Cambridge ; New York :
Cambridge University Press,
2009.
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| Subjects: |
Table of Contents:
- Humanization of recombinant antibodies
- Immunogenicity assessment of antibody therapeutics
- In vitro screening for antibody immunogenicity
- Antibody libraries from naïve V gene sources
- Antibodies from IgM libraries
- Generation and screening of synthetic human combinatorial antibody library HuCAL GOLD
- Therapeutic antibodies from XenoMouse transgenic mice
- VelocImmune : immunoglobulin variable region humanized mice
- Mechanisms of tumour cell killing by therapeutic antibodies
- Optimization of Fc domains to enhance antibody therapeutics
- Glycoengineered therapeutic antibodies
- Monoclonal antibodies for the delivery of cytotoxic drugs
- Immunotherapy with radio-immune conjugates
- Immunotherapeutic antibody fusion proteins
- Alternative antibody formats
- Single-domain antibodies
- Engineering of non-CDR loops in immunoglobulin domains
- Alternative scaffolds : expanding the options of antibodies
- Polymer fusions to increase antibody half-lives : PEGylation and other modifications
- Extending antibody half-lives with albumin
- A stem cell-based platform for the discovery and development of antitumor therapeutic antibodies to novel targets
- Antibody directed enzyme prodrug therapy (ADEPT)
- Immune privilege and tolerance - therapeutic antibody approaches
- Antibody therapeutics : business achievements and business outlook