Checkpoint responses in cancer therapy /

Bibliographic Details
Other Authors: Dai, Wei
Format: Book
Language:English
Published: Totowa, N.J. : Humana, [2008]
Series:Cancer drug discovery and development.
Subjects:
Table of Contents:
  • RB-pathway : cell cycle control and cancer therapy
  • Targeting the p53/MDM2 pathway for cancer therapy
  • DNA topoisomerases as targets for the chemotherapeutic treatment of cancer
  • Targeting ATM/ATR in the DNA damage checkpoint
  • Compounds that abrogate the G2 checkpoint
  • CDK inhibitors as anticancer agents
  • CHFR as a potential anticancer target
  • Antimicrotubule agents
  • Kinesin motor inhibitors as effective anticancer drugs
  • Targeting the spindle checkpoint in cancer chemotherapy
  • Antiproliferation inhibitors targeting aurora kinases
  • Plks as novel targets for cancer drug design
  • Do histone deacetylase inhibitors target cell cycle checkpoints that monitor heterochromatin structure?