Essential concepts in toxicogenomics /

Bibliographic Details
Other Authors: Mendrick, Donna L., Mattes, William B.
Format: Book
Language:English
Published: Totowa, N.J. : Humana, 2008.
Series:Methods in molecular biology (Clifton, N.J.) ; 460.
Subjects:
Table of Contents:
  • Toxicogenomics and classic toxicology : how to improve prediction and mechanistic understanding of human toxicity
  • Use of traditional end points and gene dysregulation to understand mechanisms of toxicity : toxicogenomics in mechanistic toxicology
  • Quality control of microarray assays for toxicogenomic and in vitro diagnostic applications
  • Role of statistics in toxicogenomics
  • Predictive toxicogenomics in preclinical discovery
  • In vivo predictive toxicogenomics
  • Bioinformatics : databasing and gene annotation
  • Microarray probe mapping and annotation in cross-species comparative toxicogenomics
  • Toxicogenomis in biomarker discovery
  • From pharmacogenomics to translational biomarkers
  • Public consortium efforts in toxicogenomics
  • Applications of toxicogenomics to nonclinical drug development : regulatory science considerations.