Pharmacogenetics of breast cancer : towards the individualization of therapy /

Bibliographic Details
Other Authors: Leyland-Jones, Brian
Format: Book
Language:English
Published: New York : Informa Healthcare, [2008]
Series:Translational medicine series ; 7.
Subjects:
Table of Contents:
  • Pharmacogenetics of breast cancer : towards the individualization of therapy
  • Pharmacology, pharmacogenetics, and pharmacoepidemiology : three P's of individualized therapy
  • Role of genetic variability in breast cancer treatment outcomes
  • The role of epigenetics in breast cancer : implications for diagnosis, prognosis, and treatments
  • Comparative genomic hybridization and copy number abnormalities in breast cancer
  • Gene expression profiling as an emerging diagnostic tool to personalize chemotherapy selection for early stage breast cancer
  • Gene expression-based predictors of prognosis and response to chemotherapy in breast cancer
  • Utilization of genomic signatures for personalized treatment of breast cancer
  • Personalized medicine by the use of microarray gene expression profiling
  • Predictive markers for targeted breast cancer treatment
  • Circulating tumor cells in individualizing breast cancer therapy
  • Individualization of endocrine therapy in breast cancer
  • TAILORx : rationale for the study design
  • Taking prognostic signatures to the clinic
  • Tissue is the issue
  • Acquisition and preservation of tissue for microarray analysis
  • Tapping into the formalin-fixed paraffin-embedded (FFPE) tissue goldmine for individualization of breast cancer treatment
  • Breast cancer stem cells and their niche : lethal seeds in lethal soil
  • Molecular imaging in individualized cancer management
  • Cancer nanotechnology for molecular profiling and individualized therapy.