Noonan syndrome and related disorders : a matter of deregulated ras signaling /

Bibliographic Details
Other Authors:	Zenker, Martin
Format:	Book
Language:	English
Published:	Basel ; New York : Karger, [2009]
Series:	Monographs in human genetics ; v. 17.
Subjects:	Genetic disorders. Ras oncogenes. Ras proteins. Noonan Syndrome > genetics. Noonan Syndrome > physiopathology. Signal Transduction. ras Proteins > genetics.

Table of Contents:

History of Noonan syndrome and related disorders
The clinical phenotype of Noonan syndrome
Molecular genetics of Noonan syndrome
Genotype-phenotype correlations in Noonan syndrome
LEOPARD syndrome : clinical aspects and molecular pathogenesis
The clinical phenotype of cardiofaciocutaneous syndrome (CFC)
Molecular causes of the cardio-facio-cutaneous syndrome
The clinical phenotype of Costello syndrome
The molecular basis of Costello syndrome
Endocrine regulation of growth and short stature in Noonan syndrome
The heart in ras-MAPK pathway disorders
Myeloproliferative disease and cancer in persons with Noonan syndrome and related disorders
Neurofibromatosis type 1-Noonan syndrome : what's the link?
Animal models for Noonan syndrome and related disorders
Towards a treatment for ras-MAPK pathway disorders