Handbook of pre-clinical continuous intravenous infusion /

Bibliographic Details
Other Authors:	Healing, Guy, 1961-, Smith, David, 1944-
Format:	Book
Language:	English
Published:	London ; New York : Taylor & Francis, 2000.
Subjects:	Toxicology > Animal models > Handbooks, manuals, etc. Toxicity testing > Handbooks, manuals, etc. Infusion therapy > Testing > Handbooks, manuals, etc. Animal experimentation > Handbooks, manuals, etc. Drug Evaluation, Preclinical. Infusions, Intravenous > methods. Animals, Laboratory.

Table of Contents:

Femoral cannulation using the jacket/harness model in the rat
Femoral cannulation using the tail cuff exteriorisation method in the rat
Tethering and the implanted button model in the rat
Multidose infusion toxicity studies in the rat
Reproductive toxicology studies by infusion in the rat
Femoral cannulation using the tail cuff model in the mouse
Multidose infusion toxicity studies in the mouse
Jugular cannulation and efficacy studies in the mouse
Femoral cannulation of the rabbit for reproductive toxicity studies
Jugular catheterisation of the rabbit for reproductive toxicity studies
Jugular cannulation in the dog
The non-ambulatory model in dog multidose infusion toxicity studies
The ambulatory model in dog multidose infusion toxicity studies
Surgical preparation and infusion of the large primate
Multidose infusion toxicity studies in the large primate
Surgical preparation and multidose infusion toxicity studies in the marmoset
Surgical preparation of the minipig
Multidose infusion toxicity studies in the minipig
Reproductive infusion toxicity studies in the minipig
Common pathological findings in continuous infusion studies
The use of mini-osmotic pumps in continuous infusion studies
The contribution of vehicles, rates of administration and volumes to infusion studies
Equipment for continuous intravenous infusion