http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
xiv, 1114 pages : illustrations (some color) ; 24 cm.
The discovery of TGF-[beta] : a historical perspective -- TGF-[beta] and the TGF-[beta] family -- Cell Biology -- TGF-[beta] : a multipotential cytokine -- Activins and inhibins -- The bone morphogenetic proteins -- Signaling -- Signaling receptors for the TGF-[beta] family -- TGF-[beta] bioavailability : latency, targeting, and activation -- Agonists and antagonists of the TGF-[beta] family ligands -- TGF-[beta] signaling from receptors to Smads -- Transcriptional control via Smads -- Growth control by TGF-[beta] : mechanisms controlling cell cycle progression and apoptosis -- Regulation of TGF-[beta] family signaling by inhibitory Smads -- Structural basis for TGF-[beta] family receptor assembly and signaling specificity -- Non-Smad TGF-[beta] signaling pathways -- Regulation of the Smad pathway by signaling cross-talk-- Differentiation, development, and physiology -- TGF-[beta] family signaling in early postimplantation of the mouse -- TGF-[beta] family signaling in Drosophila -- TGF-[beta] signaling in the nematode C. elegans -- TGF-[beta] signaling in Xenopus and zebrafish embryos -- TGF-[beta] family signaling in stem cell renewal and differentiation -- TGF-[beta] family in mesenchymal differentiation -- TGF-[beta] family in skeletal development, maintenance, and disease -- TGF-[beta] family in epithelial development -- The TGF-[beta] family in endothelial cell differentiation and cardiovascular development and function -- TGF-[beta] as a regulator of myeloid and lymphoid development and function -- TGF-[beta] family in neural and neuronal differentiation and development -- TGF-[beta] family in the reproductive tract -- Cancer and Disease -- TGF-[beta] signaling pathway and tumor suppression -- TGF-[beta] signaling in epithelial-mesenchymal transition and invasion and metastasis -- TGF-[beta] and the tumor microenvironment -- TGF-[beta] and fibrosis -- Development of TGF-[beta]-based therapeutic agents : capitalizing on TGF-[beta]'s mechanism of action and signal transduction pathways -- BMP-based therapeutics and the BMP signaling pathways
On t.p. "beta" appears as the Greek letter.
Includes bibliographical references and index.
9780879697525 (printed hardcover : alk. paper)
0879697520 (printed hardcover : alk. paper)