http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
xviii, 468 pages : illustrations ; 25 cm.
Alzheimer's disease : a hundred years of investigation -- The neuropathology of Alzheimer's disease -- Molecular genetics of Alzheimer's disease -- Biology and molecular neuropathology of [beta]-amyloid protein -- Molecular basis of tau protein pathology : role of abnormal hyperphosphorylation -- Protein misfolding, aggregation, and fibril formation : common features of cerebral and non-cerebral amyloidosis -- Apolipoprotein E, amyloid [beta] peptide, and Alzheimer's disease -- Presenilins -- Multiple transgenic mouse models for Alzheimer's disease -- Inflammation and Alzheimer's disease -- Cellular targets of amyloid [beta] peptide : potential roles in neuronal cell stress and toxicity -- Alzheimer's disease as a neurotransmitter disease -- NGF family of neurotrophins and their receptors : early involvement in the progression of Alzheimer's disease -- Clinical assessment of Alzheimer's disease -- Molecular and biological markers for Alzheimer's disease -- Current pharmacological approaches to treating Alzheimer's disease -- Amyloid-based therapiesa -- Future directions : the A[beta] amyloid pathway as the target for diagnosing, preventing, or treating Alzheimer's disease
edited by David Dawbarn, Shelley J. Allen.
Includes bibliographical references and index.
Molecular and cellular neurobiology series