What's wrong with my mouse? : behavioral phenotyping of transgenic and knockout mice /

Bibliographic Details
Main Author: Crawley, Jacqueline N.
Format: Book
Language:English
Published: Hoboken, N.J. : Wiley-Interscience, [2007]
Edition:Second edition.
Subjects:

MARC

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100 1 |a Crawley, Jacqueline N. 
245 1 0 |a What's wrong with my mouse? :  |b behavioral phenotyping of transgenic and knockout mice /  |c Jacqueline N. Crawley. 
246 3 |a What is wrong with my mouse? 
250 |a Second edition. 
264 1 |a Hoboken, N.J. :  |b Wiley-Interscience,  |c [2007] 
264 4 |c ©2007 
300 |a xvi, 523 pages :  |b illustrations ;  |c 26 cm. 
336 |a text  |2 rdacontent  |b txt 
337 |a unmediated  |2 rdamedia 
338 |a volume  |2 rdacarrier  |b nc 
504 |a Includes bibliographical references (pages 383-501) and index. 
505 0 |a Designer mice : scope and sourcebooks -- Of unicorns and chimeras : how to generate a transgenic or knockout mouse for behavioral phenotyping -- General health : give your mouse a physical -- Motor functions : open field, holeboard, rotarod, balance, grip, circadian activity, circling, stereotypy, ataxic gait, seizures -- Sensory abilities : olfaction, vision, hearing, taste, touch, nociception -- Learning and memory : Morris swim task, spatial mazes, cued and contextual conditioning, conditioned taste aversion, conditioned eyeblink, olfactory discrimination, social recognition, passive avoidance, schedule controlled operant tasks, motor learning, attention -- Feeding and drinking : daily consumption, restricted access, choice tests, microstructural analysis -- Reproductive behaviors : sexual and parental behaviors -- Social behaviors : social interaction, nesting, grooming, juvenile play, aggression -- Emotional behaviors : animal models of psychiatric disorders : mouse models of fear, anxiety, depression, schizophrenia -- Reward : self-administration of addictive drugs, conditioned place preference -- Neurodevelopment and neurodegeneration : assaying behaviors in infant, juvenile, and aged mice -- Putting it all together : choice of tests, order of testing, number of mice, equipment, housing and testing environment -- The next generation : conditional and inducible mutations, viral vector gene delivery, RNA silencing, quantitative trait loci analysis, DNA microarrays, chemical mutagenesis, gene therapy, ethical issues. 
650 0 |a Neurogenetics  |x Animal models. 
650 0 |a Transgenic mice  |x Behavior. 
650 2 |a Mice, Transgenic. 
650 2 |a Behavior, Animal. 
650 2 |a Disease Models, Animal. 
650 2 |a Genetics, Behavioral  |x methods. 
650 2 |a Mice, Knockout. 
650 2 |a Phenotype. 
999 |a MARS 
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