Toxicology of the gastrointestinal tract /

Bibliographic Details
Other Authors:	Gad, Shayne C., 1948-
Format:	Book
Language:	English
Published:	Boca Raton : CRC Press, [2007]
Series:	Target organ toxicology series.
Subjects:	Gastrointestinal system > Pathophysiology. Toxicology. Gastrointestinal Tract > drug effects. Gastrointestinal Tract > physiology. Intestinal Absorption > drug effects.

Table of Contents:

Introduction: the gastrointestinal (GI) tract as a barrier and as an absorptive and metabolic organ
Methods for the analysis of gastrointestinal function
Safety pharmacology and the GI tract
Gastronintestinal tract development and its importance in toxicology
The GI tract as major route of pharmaceutical administration
Gastrointestinal function and toxicology in canines
Absorption of macromolecules by mammalian intestinal epithelium
Peyer's patch epithelium: an imperfect barrier
Alteration of intestinal function by xenobiotic exposure: animal models
Intestinal absorption and metabolism of xenobiotics in laboratory animals
Normal and abnormal intestinal absorption by humans
Intestinal absorption and metabolism of xenobiotics in humans