Gene therapy in the central nervous system : from bench to bedside /

Bibliographic Details
Other Authors: Kaplitt, Michael G., During, Matthew J.
Format: Book
Language:English
Published: Amsterdam ; Boston : Academic Press, 2006.
Subjects:
Table of Contents:
  • Design and optimization of expression cassettes including promoter choice and regulatory elements
  • Identification of novel adeno-associated virus serotypes for use of vectors
  • HSV amplicon vectors for gene delivery to the nervous system
  • Influence of immune system on central nervous system gene transfer
  • Targeted induction of endogenous neural stem and progenitor cells : a new strategy for gene therapy of neurological disease
  • Neurosurgical targeting, delivery and infusion of gene therapy agents in the brain
  • Gene transfer for neurological disease : agencies, policies and process
  • Gene therapy for Parkinson's disease
  • Nonhuman primate models for testing gene therapy for neurodegenerative disorders
  • Delivery of molecular therapeutics into the CNS and their distribution within the brain
  • Gene therapy for CNS diseases using intrabodies
  • Gene therapy for epilepsy
  • Genetic manipulation of learning and memory
  • Psychiatric applications of viral vectors
  • Use of viral vectors to influence behavior
  • Herpes simplex vector mediated gene transfer to the peripheral nervous system for the treatment of polyneuropathy and chronic pain
  • Characteristics of pain receptors in the spinal cord using a viral vector for spatial-temporal gene targeting
  • Viral vector mediated gene therapy of pain
  • VEGE, an angiogenic factor with neurotrophic activity, useful for treatment of ALS
  • Viral vector axonal uptake and retrograde transport : mechanisms and applications
  • Gene therapy for spinal cord injury
  • Prodrug-activation gene therapy
  • Clinical trials of gene therapy for canavan disease
  • Gene therapy for the late infantile form of batten disease
  • Molecular imaging of gene therapy for neurogenetic diseases