Gene therapy in the central nervous system : from bench to bedside /

Bibliographic Details
Other Authors: Kaplitt, Michael G., During, Matthew J.
Format: Book
Language:English
Published: Amsterdam ; Boston : Academic Press, 2006.
Subjects:

MARC

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245 0 0 |a Gene therapy in the central nervous system :  |b from bench to bedside /  |c [edited by] Michael G. Kaplitt and Matthew J. During. 
264 1 |a Amsterdam ;  |a Boston :  |b Academic Press,  |c 2006. 
300 |a xiv, 355 pages :  |b illustrations (some color) ;  |c 29 cm. 
336 |a text  |2 rdacontent  |b txt 
337 |a unmediated  |2 rdamedia 
338 |a volume  |2 rdacarrier  |b nc 
504 |a Includes bibliographical references and index. 
505 0 |a Design and optimization of expression cassettes including promoter choice and regulatory elements -- Identification of novel adeno-associated virus serotypes for use of vectors -- HSV amplicon vectors for gene delivery to the nervous system -- Influence of immune system on central nervous system gene transfer -- Targeted induction of endogenous neural stem and progenitor cells : a new strategy for gene therapy of neurological disease -- Neurosurgical targeting, delivery and infusion of gene therapy agents in the brain -- Gene transfer for neurological disease : agencies, policies and process -- Gene therapy for Parkinson's disease -- Nonhuman primate models for testing gene therapy for neurodegenerative disorders -- Delivery of molecular therapeutics into the CNS and their distribution within the brain -- Gene therapy for CNS diseases using intrabodies -- Gene therapy for epilepsy -- Genetic manipulation of learning and memory -- Psychiatric applications of viral vectors -- Use of viral vectors to influence behavior -- Herpes simplex vector mediated gene transfer to the peripheral nervous system for the treatment of polyneuropathy and chronic pain -- Characteristics of pain receptors in the spinal cord using a viral vector for spatial-temporal gene targeting -- Viral vector mediated gene therapy of pain -- VEGE, an angiogenic factor with neurotrophic activity, useful for treatment of ALS -- Viral vector axonal uptake and retrograde transport : mechanisms and applications -- Gene therapy for spinal cord injury -- Prodrug-activation gene therapy -- Clinical trials of gene therapy for canavan disease -- Gene therapy for the late infantile form of batten disease -- Molecular imaging of gene therapy for neurogenetic diseases 
650 2 |a Central Nervous System Diseases  |x therapy. 
650 2 |a Genetic Therapy. 
650 2 |a Central Nervous System Diseases  |x genetics. 
650 2 |a Gene Transfer Techniques. 
650 2 |a Genetic Vectors. 
700 1 |a Kaplitt, Michael G. 
700 1 |a During, Matthew J. 
948 |a PO 10821; Blackwell 
999 |a MARS 
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