Duchenne muscular dystrophy : advances in therapeutics /

Bibliographic Details
Other Authors: Chamberlain, Jeffrey S., Rando, Thomas A.
Format: Book
Language:English
Published: New York : Taylor & Francis, 2006.
Series:Neurological disease and therapy ; v. 79.
Subjects:
Table of Contents:
  • Clinical overview of Duchenne muscular dystrophy
  • The functional biology of dystrophin : structural components and the pathogenesis of Duchenne muscular dystrophy
  • The functional biology of dystrophin : associated signaling pathways and potential targets for therapeutic intervention
  • Duchenne muscular dystrophy and Becker muscular dystrophy : diagnostic principles
  • Mutation detection
  • Protein studies in Duchenne muscular dystrophy
  • Medical management of Duchenne muscular dystrophy
  • Rehabilitation management of Duchenne muscular dystrophy
  • Orthopedic interventions in the management of Duchenne muscular dystrophy : a review of current practice and clinical outcomes
  • Therapeutic principles and challenges in Duchenne muscular dystrophy
  • Experimental pharmacologic therapies in Duchenne dystrophy : current clinical trials
  • Utrophin : the intersection between pharmacological and genetic therapy
  • Regenerative therapy
  • Cellular mediated delivery : the intersection between regenerative medicine and genetic therapy
  • Oligonucleotide-mediated exon skipping and gene editing for Duchenne muscular dystrophy
  • The intravascular delivery of naked DNA for treating Duchenne muscular dystrophy
  • Adenoviral mediated gene therapy
  • Retroviridae-based gene transfer vectors in Duchenne muscular dystrophy therapy
  • Gene therapy of muscular dystrophy using adeno-associated viral vectors : promises and limitations
  • Regional and systemic gene delivery using viral vectors