Cover Image

Amyotrophic lateral sclerosis /

Bibliographic Details
Other Authors: Mitsumoto, Hiroshi, Przedborski, Serge, Gordon, Paul H.
Format: Book
Language:English
Published: Boca Raton : Taylor & Francis, 2006.
Series:Neurological disease and therapy ; 78.
Subjects:
Amyotrophic lateral sclerosis.
Amyotrophic Lateral Sclerosis.
Table of Contents:
  • History of ALS
  • Epidemiology of ALS
  • The pathology of amyotrophic lateral sclerosis
  • The causes of sporadic amyotrophic lateral sclerosis
  • ALS clinical motor signs and symptoms
  • Frontotemporal dysfunction in amyotrophic lateral sclerosis
  • Familial ALS and genetic approaches to ALS
  • Objective markers of upper and lower motor neuron dysfunction : electrophysiological studies and neuroimaging technologies
  • Classification, diagnosis and presentation of diagnosis of ALS
  • Natural history and prognosis in amyotrophic lateral sclerosis
  • Specifying motor neuron identity in the developing spinal cord
  • Neurodegeneration in amyotrophic lateral sclerosis
  • Excitotoxicity
  • Superoxide dismutase, oxidative stress and ALS
  • Neuronal and non-neuronal cell interactions in ALS
  • Apoptosis in amyotrophic lateral sclerosis
  • Cytoskeletal proteins in the pathogenesis of ALS
  • Role of mitochondria in motor neuron degeneration in ALS
  • Environmental toxicity and ALS : novel insights from an animal model of ALS-PDC
  • Genetic causes and predisposition
  • ALS : a protein aggregate disease
  • Neuroinflammation
  • The potential of gene therapy for motor neuron diseases
  • Experimental models of motor neuron diseases
  • Screening for ALS drugs
  • Clinical trial methodology
  • The multidisciplinary care clinic : the principles and an international perspective
  • The ALS patient CARE program - North American patient CARE database
  • Symptomatic pharmacotherapy : bulbar and constitutional symptoms
  • ALS pharmacotherapy : riluzole and clinical trials
  • Rehabilitation
  • Nutritional treatment : theorectical and practical issues
  • Respiratory care in amyotrophic lateral sclerosis
  • Psychosocial care for patients with ALS and their caregivers
  • Palliative care at the end of life
  • Palliative care : family perspective
  • End-of-life decision making