DNA repair and mutagenesis /

Bibliographic Details
Other Authors: Friedberg, Errol C.
Format: Book
Language:English
Published: Washington, D.C. : ASM Press, [2006]
Edition:Second edition.
Subjects:
Table of Contents:
  • Introduction : biological responses to DNA damage
  • DNA damage
  • Introduction to mutagenesis
  • Reversal of base damage caused by UV radiation
  • Reversal of alkylation damage in DNA
  • Base excision repair
  • Nucleotide excision repair : general features and the process in prokaryotes
  • Nucleotide excision repair in eukaryotes : cell biology and genetics
  • Mechanism of nucleaotide excision repair in eukaryotes
  • Heterogeneity of nucleotide excision repair in eukaryotic genomes
  • Alternative excision repair of DNA
  • Mismatch repair
  • Repaia of mitochondrial DNA damage
  • The SOS responses of prokaryotes to DNA damage
  • Mutagenesis and translesion synthesis in prokaryotes
  • Recombinational repair, replication fork repair, and DNA damage tolerance
  • DNA damage tolerance and mutagenesis in eukaryotic cells
  • Managing DNA strand breaks in eukaryotic cells : repair pathway overview and homologous recombination
  • Managing DNA strand breaks in eukaryotic cells : nonhomologous end joining and other pathways
  • Cell cycle checkpoints : general introduction and mechanisms of DNA damage sensing
  • Cell cycle checkpoints : signal transmission and effector targets
  • Transcriptional responses to DNA damage
  • DNA damage and the regulation of cell fate
  • Xeroderma peimentosum : a disease associated with defective nucleotide excision repair or defective translesion DNA synthesis
  • Other diseases associated with defects in nucleotide excision repair of DNA
  • Diseases associated with defective responses to DNA strand breaks
  • Diseases associated with disordered DNA helicase function
  • Additional diseases associated with defective responses to DNA damage
  • Hereditary diseases that implicate defective responses to DNA damage
  • DNA polymorphisms in gatekeeper and guardian genes