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Introduction to the cellular and molecular biology of cancer /

Bibliographic Details
Main Author: Knowles, Margaret A.
Other Authors: Selby, P. (Peter)
Format: Book
Language:English
Published: New York : Oxford University Press, 2005.
Subjects:
Cancer > Molecular aspects.
Cancer cells.
Neoplasms.
Cell Transformation, Neoplastic.
Molecular Biology.
Table of Contents:
  • What is cancer
  • The causes of cancer
  • Inherited susceptibility to cancer
  • DNA repair and cancer
  • Epigenetic events in cancer
  • Molecular cytogenetics of cancer
  • Oncogenes
  • Tumour suppressor genes
  • The cancer cell cycle
  • Cellular immortalization and telomerase activation in cancer
  • Growth factors and their signaling pathways in cancer
  • Apoptosis : molecular physiology and significance for cancer therapeutics
  • Mechanisms of viral carcinogenesis
  • Cytokines and cancer
  • Hormones and cancer
  • The spread of tumours
  • Tumour angiogenesis
  • Stem cells, haemopoiesis, and leukaemia
  • Animal models of cancer
  • The immunology of cancer
  • The molecular pathology of cancer
  • From transcriptome to proteome
  • Local treatment of cancer
  • Chemotherapy
  • Radiotherapy and molecular radiotherapy
  • Monoclonal antibodies and therapy
  • Immunotherapy of cancer
  • Cancer gene therapy
  • Screening
  • Conclusions and prospects